Results 81 to 90 of about 41,849 (302)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The impact of european values on youth mindsets in the Republic of Moldova

open access: yesJournal of Social Sciences
This study was motivated by evolving perspectives in historical and anthropological discourse, which emphasize the importance of understanding collective mentalities for interpreting social transformations and assessing the feasibility of reforms.
LAZARIUC, Cristina
doaj   +1 more source

Speculative Machines and Technical Mentalities. A philosophical approach to designing the future [PDF]

open access: yes, 2015
‘Beyond their instrumental functions,’ writes Rivka Oxman in an article about design, creativity and innovation (2013), ‘advanced digital and computational environments are also becoming tools for thinking design’.
Brassett, Jamie
core   +1 more source

Mental illness and mental health [PDF]

open access: yesThe Lancet Psychiatry, 2017
Adam M, Chekroud   +2 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Do political changes regarding livestock farming, beef supply chain and Amazonian forest protection, contribute to ecological intensification? [PDF]

open access: yes, 2012
Since 2008, Amazonian agriculture has been faced with radical changes in Brazilian policies regarding agricultural land use and the preservation of forest areas.
Barbosa, Tienne   +8 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Les vertus des études des sciences : retour sur une réception française du postmodernisme en archéologie

open access: yesLes Nouvelles de l’Archéologie, 2019
In 1995, Anick Coudart and Laurent Olivier explained the French reception of postmodernism in archaeology based on the idea that scientific practices are determined by national mentalities.
Sébastien Plutniak
doaj   +1 more source

Contributors [PDF]

open access: yes, 2005
Contributors to Ethnic Studies Review, Vol. 28, No.

core   +1 more source

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