Results 91 to 100 of about 9,274 (253)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

THE CULTURE OF ROMANIAN ORGANIZATION: THE DIAGNOSIS OF THE REMANING MENTALITIES [PDF]

After 20 years of transition, the culture of Romanian companies is still dominated by some remaining block culture mentalities proper to Eastern and Central European countries. Although, from a technical point of view the transition may be regarded as an
Pandelica Ionut, Pandelica Amalia, Jianu Eugenia   +2 more
core  

The influence of social group mentalities in the Czech Republic after 1989 [PDF]

, 2007
The goal of the dissertation thesis is to describe and analyze the influence of social group mentalities on the processes of post-communist transformation in the Czech Republic after 1989.
Černý, Jiří
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Autonomy of the family in the modern world

Horyzonty Wychowania, 2017
RESEARCH OBJECTIVE: The purpose of this article is to understand autonomy of the family in the ‘modern’ world by locating the family in the historical changes that led to its present form.
Nidhi Gulati
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Yardeni (Myriam) Anti-Jewish Mentalities in Early-Modern Europe

, 1991
Azria Régine. Yardeni (Myriam) Anti-Jewish Mentalities in Early-Modern Europe. In: Archives de sciences sociales des religions, n°74, 1991. pp.
Azria, Régine
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Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Malcolm Caskill Crime and Mentalities in Early Modem England

, 2002
Rousseaux Xavier. Malcolm Caskill Crime and Mentalities in Early Modem England . In: Annales. Histoire, Sciences Sociales. 57ᵉ année, N. 6, 2002. pp.
Rousseaux, Xavier
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