Results 51 to 60 of about 9,274 (253)

Queenship, Power, and Elizabethan Mentalities in Shakespeare’s Histories

open access: yesRomanian Journal of English Studies, 2013
The paper looks at the way in which the notion of queenship - in connection or in contrast with that of kingship and royalty in general - is reflected in Shakespeare’s historical tetralogies and in Henry VIII.
Percec Dana
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The culture of book and the mentalities' history

open access: yesKnygotyra, 2003
The article deals with the theoretical and practical aspects of books. The increasing interest in the book as a phenomenon of cultural and social life is related to the development of information and mass communication networks.
Vytautas Berenis
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Social Mentalities Scale: A new measure for assessing the interpersonal motivations underlying social relationships

open access: yes, 2020
The evolutionary perspective on human emotions and motivations posits that all interpersonal interactions are shaped by an array of social mentalities, dwelling on our species' bio-behavioral disposition to pursue some evolutionarily valuable social ...
Ivan, Di Marco   +7 more
core   +1 more source

RELACIONES JESUITAS DEL TERREMOTO DE 1730: SANTIAGO, VALPARAÍSO Y CONCEPCIÓN JESUIT RELATIONS OF THE 1730 EARTHQUAKE: SANTIAGO, VALPARAÍSO AND CONCEPCIÓN

open access: yesCuadernos de Historia, 2012
Se transcriben dos informes sobre el terremoto que devastó Chile central y otras regiones cercanas en 1730. Se trata de documentos originales, relativos a las ciudades de Santiago y Concepción, y el puerto de Valparaíso.
Jaime Valenzuela Márquez
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Quarterly of Political Attitudes and Mentalities

open access: yes, 2012
European Quarterly of Political Attitudes and Mentalities Sujet : The European Quarterly on Political Attitudes and Mentalities (EQPAM) publishes original, quantitative and qualitative political analysis research articles.
Dominique Poggi
core  

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