Results 161 to 170 of about 2,386,700 (376)

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

open access: yesAdvanced Science, EarlyView.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai   +7 more
wiley   +1 more source

Contact with mentally ill people Does it effect nurses’ attitude toward mental illness?

open access: yesنشریه پرستاری ایران, 1999
B a c kgro u n d: Contact theory has been mentioned for years. Can it effect peoples' attitude a question to be answered. Objective: To determine nurses' attitude toward mental illness with different levels of contact with mentally ill people.
Khaleghparast Athari Sh.
doaj  

La pericolosità del malato di mente [PDF]

open access: yes, 2014
The article examines the complex historical, ideological, psychological and political reasons that led in Italy to the abolition of the “dangerousness of the mentally ill” as a concept in ordinary psychiatric legislation through law no. 180 of 1978 while
Lusetti, Volfango
core   +1 more source

OBUSight: Clinically Aligned Generative AI for Ophthalmic Ultrasound Interpretation and Diagnosis

open access: yesAdvanced Science, EarlyView.
OBUSight, a clinically aligned generative AI model that jointly generates reports and predicts diseases through multimodal semantic alignment, was trained and validated on a large multicenter dataset. OBUSight outperformed eight state‐of‐the‐art models, provided clinically reliable reports, enhanced diagnostic efficiency, and achieved performance ...
Xiaocong Liu   +17 more
wiley   +1 more source

Sociální začleňování duševně nemocných v podmínkách pardubického kraje [PDF]

open access: yes, 2010
The article concerns with social integration of mentally ill persons in Pardubice region. This text emphasises the cooperation between psychiatric and social services as an assumption for social integration.
Hejzlar, Petr
core   +3 more sources

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

open access: yesAdvanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li   +12 more
wiley   +1 more source

Calcium Channel Blockers Inhibit Pancreatic Neuroendocrine Neoplasms Progression via Cav1.2‐Epigenetic Circuit

open access: yesAdvanced Science, EarlyView.
Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu   +12 more
wiley   +1 more source

How is physicians' implicit prejudice against the obese and mentally ill moderated by specialty and experience? [PDF]

open access: yesBMC Med Ethics, 2022
FitzGerald C   +5 more
europepmc   +2 more sources

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