Results 101 to 110 of about 565,012 (288)
World Journal of Nuclear Medicine, 2014 We present a case of a 60-year-old white male with a history of papillary renal cell carcinoma (PRCC) status postpartial nepherectomy. He was followed-up annually with abdominal computed tomography (CT) scans to monitor for tumor recurrence.
Carina Aparici, Aung Win
doaj +1 more source
COVID-19 personal health mention detection from tweets using dual convolutional neural network. [PDF]
Expert Syst Appl, 2022 Luo L, Wang Y, Liu H.
europepmc +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
DNA promoter methylation as a diagnostic and therapeutic biomarker in gallbladder cancer
Clinical Epigenetics, 2012 Gallbladder cancer is an infrequent neoplasia with noticeable geographical variations in its incidence around the world. In Chile, it is the main cause of death owing to cancer in women over 40 years old, with mortality rates up to 16.5 per 100,000 cases.
Letelier Pablo +3 more
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Detecting Future-related Contexts of Entity Mentions
The ability to automatically identify whether an entity is referenced in a future context can have multiple applications including decision making, planning and trend forecasting. This paper focuses on detecting implicit future references in entity-centric texts, addressing the growing need for automated temporal analysis in information processing.
Prashar, Puneet +2 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The challenges and importance of structural variation detection in livestock
Frontiers in Genetics, 2014 Recent studies in humans and other model organisms have demonstrated that structural variants (SVs) comprise a substantial proportion of variation among individuals of each species.
Derek M Bickhart, George E. Liu
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Toward Mention Detection Robustness with Recurrent Neural Networks
, 2016 One of the key challenges in natural language processing (NLP) is to yield good performance across application domains and languages. In this work, we investigate the robustness of the mention detection systems, one of the fundamental tasks in information extraction, via recurrent neural networks (RNNs).
Nguyen, Thien Huu +3 more
openaire +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source