Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Gold standard, multi-genre dataset for named entity recognition and linking. [PDF]
Sci DataOlewniczak S, Szymański J.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Comparison of computed tomography and guided bronchoscopy in the diagnosis of pulmonary nodules: A systematic review and meta-analysis. [PDF]
Open Med (Wars)Wang Y, Liang X, Zhang H, Hao J, Wei M.
europepmc +1 more source
Assessing eating disorder education in U.S. medical schools: a qualitative content analysis of lecture slides. [PDF]
Eat Weight DisordLaboe AA +9 more
europepmc +1 more source
More than just appendicitis: incidental detection of a serrated polyp with malignant potential. [PDF]
J Surg Case RepMalik KA +3 more
europepmc +1 more source
Detection of Candida spp. from peritoneal swabs indicate worse outcome in patients with perforated peptic ulcer: revisiting a longstanding debate. [PDF]
BMC SurgKoca F +9 more
europepmc +1 more source
Structural damage detection and safety assessment method based on machine vision and machine learning. [PDF]
PLoS OneWang S, Li M, Le D.
europepmc +1 more source