Results 201 to 210 of about 6,199 (251)
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An analysis of the ‘legal high’ mephedrone

Bioorganic & Medicinal Chemistry Letters, 2010
'Legal highs' are compounds, plant or fungal material which can be readily bought from the internet without legal restriction and the single chemicals may be structurally related to illegal drugs of abuse such as the amphetamines. Several recent deaths in the UK have been attributed to these legal highs and unfortunately there is little chemical or ...
Gibbons, Simon, Zloh, Mire
openaire   +3 more sources

Effect of Mephedrone Exposure During Gestation on the Morphometrical Parameters of the Cerebellum in the Balb/C Mouse Offsprings

Archives of Neuroscience
Background: Addiction, particularly to synthetic stimulants like mephedrone, poses significant challenges for both treatment and societal health. Mephedrone, a cathinone derivative, is increasingly misused and has been shown to affect brain function ...
Saeed Karimabadi   +2 more
semanticscholar   +1 more source

Implementation of Modified D-SPE Method for Simultaneous Quantification of Methamphetamine & Mephedrone Using LC-MS/MS

Letters in Applied NanoBioScience
New psychoactive substances (NPS) emerge on the drug market as a means to evade controlled substance legislation. Among these substances, mephedrone (MPDn) and methamphetamine (MTPn), belonging to the amphetamine category, have gained popularity as ...

semanticscholar   +1 more source

Post-mortem distribution of mephedrone and its metabolites in body fluids and organ tissues of an intoxication case.

Journal of Pharmaceutical and Biomedical Analysis, 2021
New psychoactive substances (NPS) are substances that continue to appear on the drug market to bypass controlled substance legislation. Mephedrone or 4-methylmethcathinone is becoming the most popular new psychoactive substance among youth as a ...
F. Palazzoli   +4 more
semanticscholar   +1 more source

Mephedrone and other cathinones

Current Opinion in Psychiatry, 2014
New designer drugs are constantly emerging in the illicit drug market and represent a significant health problem. A very popular class comprises synthetic cathinones, β-keto amphetamine analogues, endowed with psychostimulant properties. The aim of this review is to discuss the recent progress in our understanding of how cathinones act and the health ...
openaire   +2 more sources

Mephedrone Concentrations in Cases of Clinical Intoxication.

Current Pharmaceutical Design, 2018
Mephedrone (4-methylmethcathinone, 4-MMC), a ring-substituted synthetic cathinone derivative has become established as a permanent illicit drug in the dynamic new psychoactive substances (NPS) scene.This review summarizes current knowledge on mephedrone concentrations in biological samples from cases of acute intoxications (fatal and non-fatal ...
E. Papaseit   +4 more
semanticscholar   +3 more sources

Development of an Analytical Method for Mephedrone and Methamphetamine Using Gas Chromatography-Mass Spectrometry (GC-MS)

International Journal of Drug Delivery Technology
This article presents the properties of synthetic psychostimulants mephedrone and methamphetamine as well as the results of developing gas chromatography–mass spectrometry (GC-MS) methods for their identification from biological matrices.
Abdukhalikova Nargiza Uktamovna   +3 more
semanticscholar   +1 more source

Detection of mephedrone and its metabolites in fingerprints from a controlled human administration study by liquid chromatography-tandem mass spectrometry and paper spray-mass spectrometry.

In Analysis, 2020
The use of synthetic stimulants, including designer cathinones, remains a significant concern worldwide. Thus, the detection and identification of synthetic cathinones in biological matrices is of paramount importance for clinical and forensic ...
J. Czerwińska   +8 more
semanticscholar   +1 more source

[Mephedrone].

Revue medicale de Liege, 2012
Mephedrone is a designer drug recently appeared on the belgian market of the drugs of misuse. The aim of this journal paper is to provide a review on the available data about mephedrone and to call the attention of the first line practitioners who will have to face this emerging problem.
X, Bertrand, M, Gensburger, E, Steckx
openaire   +1 more source

Mephedrone toxicity in a Scottish emergency department

Emergency Medicine Journal, 2010
To review and improve the evidence base regarding the toxic effects of Mephedrone, a cathinone derivative which was first believed to have been synthesised and propagated in 2007. On the 7th April 2010 the Misuse of Drugs Act 1971 (Amendment) Order 2010 was passed, declaring 4-Methylmethcathinone and other substituted cathinones Class B drugs as of 16 ...
Luke, Regan   +2 more
openaire   +2 more sources

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