Results 1 to 10 of about 6,369 (264)

Synthetic Cathinones: Recent Developments, Enantioselectivity Studies and Enantioseparation Methods

Molecules, 2022
New psychoactive substances represent a public health threat since they are not controlled by international conventions, are easily accessible online and are sold as a legal alternative to illicit drugs. Among them, synthetic cathinones are widely abused
Ana Sofia da Costa Almeida, BÁrbara Silva, Paula Guedes de Pinho   +2 more
exaly   +3 more sources

Unusual Case of Fatal Virtual Chemsex Session Involving 3-Chloromethcathinone (3-CMC) [PDF]

Toxics
Synthetic cathinones, frequently used in chemsex, are difficult to identify in postmortem blood due to their short half-life and in vitro degradation. This unusual case of chemsex involving 3-CMC highlights the importance of freezing a blood aliquot and ...
Anne-Laure Pélissier-Alicot, Nicolas Fabresse, Antoine Petitcollin, Rémi Costagliola, Camille Dubertrand, Valérie Baillif-Couniou, Caroline Sastre, Marie-Dominique Piercecchi, Georges Leonetti   +8 more
doaj   +2 more sources

The Effect of Selected Cathinones on Natural Cell Membranes: Microelectrophoretic Methods [PDF]

Molecules
Synthetic cathinones are cathinone analogues that humans have artificially created. The first compounds appeared on the European market in 2005. They belong to a class of drugs called stimulants, classified as new psychoactive substances.
Anna Trynda, Katarzyna Karwowska, Weronika Karpowicz, Katarzyna Kazimierska-Drobny, Aneta D. Petelska   +4 more
doaj   +2 more sources

From dust till dawn: patterns, motives, and risks of using smokable synthetic cathinones [PDF]

Harm Reduction Journal
Background Synthetic cathinones that are primarily smoked—such as pyrovalerone-type compounds, including MDPV, MDPHP, α-PHP, and α-PHiP, often referred to as “Monkey Dust”—have raised growing concern in clinical and harm reduction contexts due to their ...
Antonia Bendau, Paale Bournot, Felix Betzler, Christopher Clay, Jonas Desaga, Twyla Michnevich   +5 more
doaj   +2 more sources

From Psychoactivity to Antimicrobial Agents: Multifaceted Applications of Synthetic Cathinones and Catha edulis Extracts [PDF]

Molecules
The emergence of new psychoactive substances (NPS) in the global drug market since the 2000s has posed major challenges for regulators and law enforcement agencies.
Celia María Curieses Andrés, José Manuel Pérez de la Lastra, Elena Bustamante Munguira, Celia Andrés Juan, Eduardo Pérez-Lebeña   +4 more
doaj   +2 more sources

Acute pharmacological effects of α-PVP in humans: a naturalistic observational study [PDF]

Frontiers in Pharmacology
IntroductionAlpha-pyrrolidinopentiophenone (α-PVP) is a commonly consumed analogue of pyrovalerone, a synthetic cathinone with psychostimulant properties similar to those of 3,4-Methylenedioxypyrovalerone (MDPV) and cocaine.
Georgina De la Rosa, Georgina De la Rosa, Esther Papaseit, Esther Papaseit, Olga Hladun, Olga Hladun, Lourdes Poyatos, Dolly Andrea Caicedo, Dolly Andrea Caicedo, Martha Catalina Argote, Martha Catalina Argote, Soraya Martín, Mireia Ventura, Nunzia La Maida, Annagiulia Di Trana, Silvia Graziano, Simona Pichini, Magí Farré, Magí Farré, Clara Pérez-Mañá, Clara Pérez-Mañá   +20 more
doaj   +2 more sources

Research Progress on the Effect of Synthetic Cathinones on Animal Behavior [PDF]

Fayixue Zazhi, 2021
Synthetic cathinones are a class of new psychoactive substances with a structure similar to amphetamine drugs, which can produce excitatory effects similar to drugs such as amphetamine and cocaine after being taken.
HUANG Zhi-bin, CAI Juan, LIN Ze-bin, et al.
doaj   +1 more source

Simple Analytical Strategy for Screening Three Synthetic Cathinones (α-PVT, α-PVP, and MDPV) in Oral Fluids

Analytica, 2022
Synthetic cathinones are analogue compounds of the plant based stimulant cathinone. Its use, abuse, and related consumption complications have steadily increased in the last years.
André M. Segurado, Samir M. Ahmad, Nuno R. Neng, Margarida M. Maniés-Sequeira, Helena Gaspar, José Manuel F. Nogueira   +5 more
doaj   +1 more source

Metabolic stability and metabolite profiling of emerging synthetic cathinones

Frontiers in Pharmacology, 2023
Synthetic cathinones constitute the second largest groups of new psychoactive substances (NPS), which are especially popular among adolescents and young adults.
Rita P. Lopes, Rita P. Lopes, Raquel A. Ferro, Raquel A. Ferro, Margarida Milhazes, Margarida Figueira, Maria João Caldeira, Alexandra M. M. Antunes, Helena Gaspar, Helena Gaspar   +9 more
doaj   +1 more source

Metabolic Profile of Four Selected Cathinones in Microsome Incubations: Identification of Phase I and II Metabolites by Liquid Chromatography High Resolution Mass Spectrometry

Frontiers in Chemistry, 2021
Consumption of synthetic cathinones, the second largest class of new psychoactive substances (NPS) reported worldwide, represents a serious public health risk. One of the biggest challenges created by the rapid spread of NPS on the illegal drug market is
Beatriz T. Lopes, Beatriz T. Lopes, Maria João Caldeira, Helena Gaspar, Helena Gaspar, Alexandra M. M. Antunes   +5 more
doaj   +1 more source