Deep Learning-Enabled MS/MS Spectrum Prediction Facilitates Automated Identification Of Novel Psychoactive Substances. [PDF]
Anal Chem, 2023 The market for illicit drugs has been reshaped by the emergence of more than 1100 new psychoactive substances (NPS) over the past decade, posing a major challenge to the forensic and toxicological laboratories tasked with detecting and identifying them ...
Wang F +13 more
europepmc +2 more sources
Reports of Adverse Events Associated with Use of Novel Psychoactive Substances, 2017-2020: A Review. [PDF]
J Anal Toxicol, 2022 An important role of modern forensic and clinical toxicologists is to monitor the adverse events of novel psychoactive substances (NPS). Following a prior review from 2013 to 2016, this critical literature review analyzes and evaluates published case ...
Mohr ALA +7 more
europepmc +2 more sources
Deadly confusion of novel psychoactive substances: fatal outcome of ADB-BUTINACA mislabeled as 3',4'-methylenedioxy-α-pyrrolidinohexiophenone. [PDF]
Forensic ToxicolA powder found at a fatality scene, labeled as the synthetic cathinone 3’,4’-methylenedioxy-α-pyrrolidinohexiophenone (MDPHP) and most likely smoked using a crack pipe, was analyzed.
Zschiesche A +9 more
europepmc +2 more sources
Novel psychoactive substances. [PDF]
Br J Gen Pract, 2016 Gilani does well to highlight the increasing and concerning use of novel psychoactive substances (NPS) in the UK.1 We have seen the damaging and unpredictable effects of synthetic cannabinoids in prisons …
Brew I.
europepmc +7 more sources
An emerging trend in Novel Psychoactive Substances (NPSs): designer THC. [PDF]
J Cannabis ResSince its discovery as one of the main components of cannabis and its affinity towards the cannabinoid receptor CB1, serving as a means to exert its psychoactivity, Δ^9-tetrahydrocannabinol (Δ^9-THC) has inspired medicinal chemists throughout history to ...
Caprari C +4 more
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Novel Psychoactive Substances: The Razor's Edge between Therapeutical Potential and Psychoactive Recreational Misuse. [PDF]
Medicines (Basel), 2022 Background: Novel psychoactive substances (NPS) are compounds of natural and synthetic origin, similar to traditional drugs of abuse. NPS are involved in a contemporary trend whose origin lies in a thinner balance between legitimate therapeutic drug ...
Correia B +4 more
europepmc +2 more sources
Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders. [PDF]
Int J Environ Res Public Health, 2022 This study aims to determine prevalence and frequency of use of novel psychoactive substances (NPS) and to identify the factors associated with NPS use in an Italian sample of patients diagnosed with substance use disorder (SUD).
Dal Farra D +9 more
europepmc +2 more sources
Trends in Mortality From Novel Psychoactive Substances as "Legal Highs": Gender Differences in Manner of Death and Implications for Risk Differences for Women. [PDF]
Front Psychiatry, 2022 Introduction This study aimed to examine drug-related deaths in the UK in which novel psychoactive substances (NPS) are an implicated substance, and to focus on female deaths in comparison with male deaths.
Webb L, Shi X, Goodair C, Cheeta S.
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STNGS: a deep scaffold learning-driven generation and screening framework for discovering potential novel psychoactive substances. [PDF]
Brief BioinformThe supervision of novel psychoactive substances (NPSs) is a global problem, and the regulation of NPSs was heavily relied on identifying structural matches in established NPSs databases.
Liu D +13 more
europepmc +2 more sources
Stimulant and hallucinogenic novel psychoactive substances; an update [PDF]
Expert Review of Clinical Pharmacology, 2023 Introduction The renewed interest in considering a range of stimulants, psychedelics and dissociatives as therapeutics emphasizes the need to draft an updated overview of these drugs’ clinical and pharmacological issues.
F. Schifano +3 more
semanticscholar +4 more sources