Results 41 to 50 of about 9,104 (252)

Case Report: Treatment of Kratom Use Disorder With a Classical Tricyclic Antidepressant

Frontiers in Psychiatry, 2021
Kratom or Mitragyna speciosa (Korth.) is an evergreen tree of the coffee family native to South-East Asia and Australasia. It is used by locals recreationally to induce stimulant and sedative effects and medically to soothe pain and opiate withdrawal ...
Alessandro E. Vento, Alessandro E. Vento, Simone de Persis, Sergio De Filippis, Fabrizio Schifano, Flavia Napoletano, John M. Corkery, Georgios D. Kotzalidis, Georgios D. Kotzalidis   +8 more
doaj   +1 more source

The Novel Psychoactive Substances Epidemic: a Scientometric Perspective

Addiction Neuroscience, 2022
Abstract The unprecedented proliferation of novel psychoactive substances (NPS) in the illicit drug market has been a public health concern since their emergence in the 2000s. Their consumption can pose a severe health risks as their mechanism of action is poorly understood and their level of toxicity is high mainly due to the diffusion
Michelle Jin Yee Neoh, Alessandro Carollo, Mengyu Lim, Ornella Corazza, Aurora Coppola, Gianluca Esposito   +5 more
openaire   +3 more sources

Benzodiazepine Boom: Tracking Etizolam, Pyrazolam, and Flubromazepam from Pre-UK Psychoactive Act 2016 to Present Using Analytical and Social Listening Techniques

Pharmacy
Introduction: The designer benzodiazepine (DBZD) market continues to expand whilst evading regulatory controls. The widespread adoption of social media by pro-drug use communities encourages positive discussions around DBZD use/misuse, driving demand ...
Anthony Mullin, Mark Scott, Giorgia Vaccaro, Giuseppe Floresta, Davide Arillotta, Valeria Catalani, John M. Corkery, Jacqueline L. Stair, Fabrizio Schifano, Amira Guirguis   +9 more
doaj   +1 more source

Psychedelic Fauna for Psychonaut Hunters: A Mini-Review

Frontiers in Psychiatry, 2018
Currently different classes of psychoactive substances are easily available for abuse, including several hundred novel psychoactive substances (NPS).
Laura Orsolini, Laura Orsolini, Laura Orsolini, Michela Ciccarese, Duccio Papanti, Domenico De Berardis, Domenico De Berardis, Domenico De Berardis, Amira Guirguis, John M. Corkery, Fabrizio Schifano   +10 more
doaj   +1 more source

Priapism associated with novel psychoactive substance abuse [PDF]

Central European Journal of Urology, 2015
Priapism is a time-dependent emergency, which can lead to marked adverse effects on erectile function. We present the case of a patient with bipolar disorder who consumed a novel psychoactive substance, as well as an illegal substitute for sildenafil citrate. History revealed erectile dysfunction most likely secondary to hyperprolactinaema.
Jones, Patrick, Rai, Bhavan Prasad, Doig, Stuart, Ahammed, Niyaz   +3 more
openaire   +2 more sources

Novel Opioids: Systematic Web Crawling Within the e-Psychonauts’ Scenario

Frontiers in Neuroscience, 2020
BackgroundA wide range of novel psychoactive substances (NPSs) are regularly searched and discussed online by e-psychonauts. Among NPSs, the range of prescription/non-prescription opioids (fentanyl and non-fentanyl analogs) and herbal derivatives ...
Davide Arillotta, Davide Arillotta, Fabrizio Schifano, Flavia Napoletano, Caroline Zangani, Caroline Zangani, Liam Gilgar, Amira Guirguis, Amira Guirguis, John Martin Corkery, Eugenio Aguglia, Alessandro Vento, Alessandro Vento, Alessandro Vento   +13 more
doaj   +1 more source

Use of Medicinal Cannabis and Synthetic Cannabinoids in Post-Traumatic Stress Disorder (PTSD): A Systematic Review

Medicina, 2019
Background and Objectives: Post-traumatic stress disorder (PTSD) is a common psychiatric disorder resulting from a traumatic event, is manifested through hyperarousal, anxiety, depressive symptoms, and sleep disturbances.
Laura Orsolini, Stefania Chiappini, Umberto Volpe, Domenico De Berardis, Roberto Latini, Gabriele Duccio Papanti, John Martin Corkery   +6 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Focus on Over-the-Counter Drugs' Misuse: A Systematic Review on Antihistamines, Cough Medicines, and Decongestants

Frontiers in Psychiatry, 2021
Background: Over the past 20 years or so, the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes.
Fabrizio Schifano, Stefania Chiappini, Stefania Chiappini, Andrea Miuli, Alessio Mosca, Maria Chiara Santovito, John M. Corkery, Amira Guirguis, Mauro Pettorruso, Massimo Di Giannantonio, Giovanni Martinotti   +10 more
doaj   +1 more source

A Novel CsYABBY3‐CsAS1 Feedback Loop Coordinates Trichome Differentiation and Cannabinoid Biosynthesis in Cannabis sativa L.

Advanced Science, EarlyView.
A novel transcriptional module involving CsYABBY3 and CsAS1 is identified to regulate cannabinoid biosynthesis and trichome development. These factors mutually activate each other and form a protein complex via a conserved residue, acting synergistically to amplify metabolic flux through a coordinate feed‐forward mechanism.
Xuewen Zhu, Yaolei Mi, Xue Cao, Weiqiang Chen, Pucheng Fan, Jing Wang, Yiming Zhang, Wei Yang, Huihua Wan, Shanshan Chen, Xiangxiao Meng, Jun Li, Shuo Shen, Mingkun Huang, Xiaoyu Zhang, Ming Luo, Shilin Chen, Zhichao Xu, Wei Sun   +18 more
wiley   +1 more source