Results 41 to 50 of about 4,816,902 (277)

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Benzodiazepine Boom: Tracking Etizolam, Pyrazolam, and Flubromazepam from Pre-UK Psychoactive Act 2016 to Present Using Analytical and Social Listening Techniques

Pharmacy
Introduction: The designer benzodiazepine (DBZD) market continues to expand whilst evading regulatory controls. The widespread adoption of social media by pro-drug use communities encourages positive discussions around DBZD use/misuse, driving demand ...
Anthony Mullin, Mark Scott, Giorgia Vaccaro, Giuseppe Floresta, Davide Arillotta, Valeria Catalani, John M. Corkery, Jacqueline L. Stair, Fabrizio Schifano, Amira Guirguis   +9 more
doaj   +1 more source

Psychedelic Fauna for Psychonaut Hunters: A Mini-Review

Frontiers in Psychiatry, 2018
Currently different classes of psychoactive substances are easily available for abuse, including several hundred novel psychoactive substances (NPS).
Laura Orsolini, Laura Orsolini, Laura Orsolini, Michela Ciccarese, Duccio Papanti, Domenico De Berardis, Domenico De Berardis, Domenico De Berardis, Amira Guirguis, John M. Corkery, Fabrizio Schifano   +10 more
doaj   +1 more source

Priapism associated with novel psychoactive substance abuse [PDF]

Central European Journal of Urology, 2015
Priapism is a time-dependent emergency, which can lead to marked adverse effects on erectile function. We present the case of a patient with bipolar disorder who consumed a novel psychoactive substance, as well as an illegal substitute for sildenafil citrate. History revealed erectile dysfunction most likely secondary to hyperprolactinaema.
Jones, Patrick, Rai, Bhavan Prasad, Doig, Stuart, Ahammed, Niyaz   +3 more
openaire   +2 more sources

Use of Medicinal Cannabis and Synthetic Cannabinoids in Post-Traumatic Stress Disorder (PTSD): A Systematic Review

Medicina, 2019
Background and Objectives: Post-traumatic stress disorder (PTSD) is a common psychiatric disorder resulting from a traumatic event, is manifested through hyperarousal, anxiety, depressive symptoms, and sleep disturbances.
Laura Orsolini, Stefania Chiappini, Umberto Volpe, Domenico De Berardis, Roberto Latini, Gabriele Duccio Papanti, John Martin Corkery   +6 more
doaj   +1 more source

Novel Opioids: Systematic Web Crawling Within the e-Psychonauts’ Scenario

Frontiers in Neuroscience, 2020
BackgroundA wide range of novel psychoactive substances (NPSs) are regularly searched and discussed online by e-psychonauts. Among NPSs, the range of prescription/non-prescription opioids (fentanyl and non-fentanyl analogs) and herbal derivatives ...
Davide Arillotta, Davide Arillotta, Fabrizio Schifano, Flavia Napoletano, Caroline Zangani, Caroline Zangani, Liam Gilgar, Amira Guirguis, Amira Guirguis, John Martin Corkery, Eugenio Aguglia, Alessandro Vento, Alessandro Vento, Alessandro Vento   +13 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Head shops and new psychoactive substances: a public health perspective.

, 2023
In 2010, Ireland found itself at the eye of an international storm as a network of head shops emerged selling new psychoactive substances (NPS) and Irish youth rapidly became the heaviest users of NPS in Europe.
Smyth, Bobby P
core   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

A Whole City Response to the Use of Novel Psychoactive Substances (NPS) by Young People in Newcastle-upon-Tyne [PDF]

, 2015
In recent years, Novel Psychoactive Substances (NPS) (otherwise known as ‘legal highs’) have posed an increasingly significant problem for practitioners and policy makers due to their widespread availability, largely unknown chemical composition and ...
Irving, Adele, Parker, Chris, Soppitt, Sarah   +2 more
core