Results 41 to 50 of about 76,888 (317)

The Psychonauts’ Benzodiazepines; Quantitative Structure-Activity Relationship (QSAR) Analysis and Docking Prediction of Their Biological Activity

open access: yesPharmaceuticals, 2021
Designer benzodiazepines (DBZDs) represent a serious health concern and are increasingly reported in polydrug consumption-related fatalities. When new DBZDs are identified, very limited information is available on their pharmacodynamics.
Valeria Catalani   +6 more
doaj   +1 more source

Head shops and new psychoactive substances: a public health perspective. [PDF]

open access: yes, 2023
In 2010, Ireland found itself at the eye of an international storm as a network of head shops emerged selling new psychoactive substances (NPS) and Irish youth rapidly became the heaviest users of NPS in Europe.
Smyth, Bobby P
core   +1 more source

A Focus on Abuse/Misuse and Withdrawal Issues with Selective Serotonin Reuptake Inhibitors (SSRIs): Analysis of Both the European EMA and the US FAERS Pharmacovigilance Databases

open access: yesPharmaceuticals, 2022
Despite increasing reports, antidepressant (AD) misuse and dependence remain underestimated issues, possibly due to limited epidemiological and pharmacovigilance evidence.
Stefania Chiappini   +5 more
doaj   +1 more source

No prescription? No problem: A qualitative study investigating self-medication with novel psychoactive substances (NPS).

open access: yesThe International journal on drug policy, 2023
BACKGROUND The proliferation of Novel Psychoactive Substances (NPS) presents a challenge for global drug policy. The ease of online drug purchase and the emergence of the dark web have created new avenues for the growth of NPS.
Tayler Holborn, F. Schifano, P. Deluca
semanticscholar   +1 more source

Novel psychoactive substances: a novel clinical challenge [PDF]

open access: yesBMJ Case Reports, 2013
The recreational use of novel psychoactive substances in the UK has increased markedly within the last decade. The variety of new substances synthesised and sold as ‘legal’, often under the pretence of being ‘plant food’ or ‘bath salts’ is similarly increasing. This presents challenges to clinicians: they may be unaware of these substances or unable to
Christopher Daniel, Smith   +2 more
openaire   +2 more sources

Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signalling [PDF]

open access: yes, 2015
Novel psychoactive substances are newly used designer drugs ("internet drugs", "research chemicals", "legal highs") potentially posing similar health risks to classic illicit substances. Chemically, many novel psychoactive substances can be classified as
Liechti, Matthias E., Matthias Liechti
core   +1 more source

What about “Pharming”? Issues Regarding the Misuse of Prescription and Over-the-Counter Drugs

open access: yesBrain Sciences, 2020
Recently, a range of prescription and over-the-counter (OTC) drugs have emerged as being used recreationally, either on their own or in combination with other substances, both licit and illicit, including new psychoactive substances (NPS).
Stefania Chiappini, Fabrizio Schifano
doaj   +1 more source

Analysing social media data to understand self-medication with novel psychoactive substances (NPS) [PDF]

open access: yes, 2022
A content analysis using data from Reddit to explore self-medication practices with novel psychoactive substances ...
Tayler Holborn
core   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

Novel Psychoactive Substances (NPS) profile in South Gloucestershire [PDF]

open access: yes, 2014
Novel Psychoactive Substances (NPS) are chemical substances that have been synthesised to cause similar reactions to those produced by taking conventional drugs. The report estimates the prevalence of NPS use across South Gloucestershire.
Ismail, Nasrul
core   +1 more source

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