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High prevalence of prescription of psychotropic drugs for older patients in a general hospital
BMC Pharmacology and Toxicology, 2017 Background Many elderly patients receive psychotropic drugs. Treatment with psychotropic agents is associated with serious side effects including an increased risk of falls and fractures.
Inken Arnold +7 more
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Influence of psychotropic drugs on driving skils
Zdravniški Vestnik, 2013 Psychotropic drugs could influence psychophysical performance and driving skills. Impaired psychophysical performance can therefore represents an important cause of traffic accidents.
Brigita Novak Šarotar, Peter Pregelj
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Analysis of prescription and dispensation of psychotropic medications in two cities in the State of São Paulo, Brazil [PDF]
Brazilian Journal of Psychiatry, 2002 OBJECTIVES: To investigate the prescription and dispensation of psychotropic medications through the analysis of the prescriptions/notices kept at various institutions in two cities in the state of São Paulo. METHODS: The prescriptions kept at drugstores,
Ana Regina Noto +11 more
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Chinese Medicine, 2023 Background The clinical applications of dispensing granules (DG) have increased dramatically. However, it is controversial whether the DG has the same quality and efficacy compared with traditional decoction (TD).
Huanhuan Yu +7 more
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The Role of Epigenetic Modifications in Neurotoxicity Induced by Neonatal General Anesthesia
Frontiers in Molecular Neuroscience, 2022 It has been widely demonstrated by numerous preclinical studies and clinical trials that the neonates receiving repeated or long-time general anesthesia (GA) could develop prolonged cognitive dysfunction.
Lin-Hui Ma +8 more
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Treatment of depression: Are psychotropic drugs appropriately dosed in women and in the elderly? Dosages of psychotropic drugs by sex and age in routine clinical practice [PDF]
, 2022 BACKGROUND Several researchers have shown higher concentration-dose ratios of psychotropic drugs in women and the elderly. Therefore, lower dosages of psychotropic drugs may be recommended in women and the elderly.
Stassen, Hans +19 more
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Cell Death Discovery, 2021 Alzheimer’s disease (AD) is characterized by aberrant accumulation of extracellular β-amyloid (Aβ) peptides in the brain. Soluble Aβ oligomers are thought to be the most neurotoxic species and are correlated with cognitive dysfunction in early AD ...
Xiu Yang +13 more
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Acta Pharmaceutica Sinica B, 2023 Colorectal cancer (CRC) is a type of malignant tumor that seriously threatens human health and life, and its treatment has always been a difficulty and hotspot in research.
Haowei Liu +5 more
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A common neuronal ensemble in nucleus accumbens regulates pain-like behaviour and sleep
Nature Communications, 2023 A comorbidity of chronic pain is sleep disturbance. Here, we identify a dual-functional ensemble that regulates both pain-like behaviour induced by chronic constrictive injury or complete Freund’s adjuvant, and sleep wakefulness, in the nucleus accumbens
Haiyan Sun +8 more
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Cell Reports, 2023 Summary: The neural circuit mechanisms underlying postoperative cognitive dysfunction (POCD) remain elusive. We hypothesized that projections from the medial prefrontal cortex (mPFC) to the amygdala are involved in POCD.
Xiao-Yu Sun +7 more
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