Results 1 to 10 of about 100,757 (302)

Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment

eLife
Memory impairment in chronic pain patients is substantial and common, and few therapeutic strategies are available. Chronic pain-related memory impairment has susceptible and unsusceptible features.
Mengqiao Cui, Xiaoyuan Pan, Zhijie Fan, Shulin Wu, Ran Ji, Xianlei Wang, Xiangxi Kong, Zhou Wu, Lingzhen Song, Weiyi Song, Jun-Xia Yang, Hongjie Zhang, Hongxing Zhang, Hai-Lei Ding, Jun-Li Cao   +14 more
doaj   +1 more source

Pregabalin: a range of misuse-related unanswered questions [PDF]

, 2019
© 2019 The Authors.
Chiappini, Stephania, Schifano, Fabrizio
core   +2 more sources

Anesthetic-mediated cardioprotection: from molecular mechanisms to clinical translation challenges

Frontiers in Physiology
Anesthetics have long been recognized as essential pharmacological agents for surgical procedures, primarily valued for their ability to induce unconsciousness and provide analgesia.
Tingting Fu, Xiao Jia, Can Tang, Dan Yu, Hui Zhou, Xinghe Wang, Xinghe Wang, Su Liu, Su Liu, Kunwei Wu, Kunwei Wu   +10 more
doaj   +1 more source

How did the use of psychotropic drugs change during the Great Recession in Portugal? A follow-up to the National Mental Health Survey

BMC Psychiatry, 2020
Background Research suggests that economic recessions might be associated with a higher use of psychotropic drugs, but literature is scarce and contradictory in identifying the most vulnerable groups. This study aims to assess possible changes in the use
Manuela Silva, Ana Antunes, Sofia Azeredo-Lopes, Graça Cardoso, Miguel Xavier, Benedetto Saraceno, José Miguel Caldas-de-Almeida   +6 more
doaj   +1 more source

Can student mental health nurses be prepared for medicines management? [PDF]

, 2014
Aim This paper reports on an evaluation of the Medicines with Respect project, which implemented a stepped approach to education and training in medicines management (MM) for mental health nurses (MHNs). Method In the retrospective qualitative study,
Hemingway S, Hemingway S, Mutsatsa S, Newell R, Turner J   +4 more
core   +1 more source

NAT10 inhibition alleviates astrocyte autophagy by impeding ac4C acetylation of Timp1 mRNA in ischemic stroke

Acta Pharmaceutica Sinica B
Although a single nucleotide polymorphism for N-acetyltransferase 10 (NAT10) has been identified in patients with early-onset stroke, the role of NAT10 in ischemic injury and the related underlying mechanisms remains elusive.
Li Yang, Xiaotong Li, Yaxuan Zhao, Hao Chen, Can Wang, Angrong Wu, Xintong Guo, Yue Huang, Qihui Wang, Lingyun Hao, Xiaowen Li, Ying Ji, Jin Ban, Guangtian Wang, Junli Cao, Zhiqiang Pan   +15 more
doaj   +1 more source

Medicaid Policy Changes in Mental Health Care and Their Effect on Mental Health Outcomes [PDF]

In recent years, Medicaid has experienced a dramatic increase in spending on prescription drugs in general and psychotropic medications in particular.
Alison Cuellar, Sara Markowitz
core  

Volatile substance misuse among high school students in South America [PDF]

, 2011
This article summarizes data from a 2004 study of over 300,000 high school students (aged 13–18 years) in nine South American countries. A probabilistic sample targeted urban secondary schools, utilizing a self-administered questionnaire on prevalence ...
Delva, Jorge, Hynes-Dowell, Marya, Mateu-Gelabert, Pedro, Taunhauser Barros, Helena Maria   +3 more
core   +1 more source

Lysosomes finely control macrophage inflammatory function via regulating the release of lysosomal Fe2+ through TRPML1 channel

Nature Communications
Lysosomes are best known for their roles in inflammatory responses by engaging in autophagy to remove inflammasomes. Here, we describe an unrecognized role for the lysosome, showing that it finely controls macrophage inflammatory function by manipulating
Yanhong Xing, Meng-meng Wang, Feifei Zhang, Tianli Xin, Xinyan Wang, Rong Chen, Zhongheng Sui, Yawei Dong, Dongxue Xu, Xingyu Qian, Qixia Lu, Qingqing Li, Weijie Cai, Meiqin Hu, Yuqing Wang, Jun-li Cao, Derong Cui, Jiansong Qi, Wuyang Wang   +18 more
doaj   +1 more source

Guidelines for the recording and evaluation of pharmaco-EEG data in man: the International Pharmaco-EEG Society (IPEG) [PDF]

, 2012
The International Pharmaco-EEG Society (IPEG) presents updated guidelines summarising the requirements for the recording and computerised evaluation of pharmaco-EEG data in man.
BABILONI, CLAUDIO, Boeijinga PH, Brunovsky M, Drinkenburg WH, Ffytche DH, Freeman J, Hegerl U, Hirata K, IPEG Pharmaco EEG Guidelines C.o.m.m.i.t.t.e.e. Collaborators, Jobert M, Kinoshita T, Knott VJ, Lopes Da Silva FH, Matousek M, Mucci A, Nottage JF, Olbrich S, Prichep LS, Ruigt GS, Saletu B, Stancak A, Strik WK, van Gerven JM, Wilson FJ, Wise RG   +24 more
core   +1 more source