Results 11 to 20 of about 42,511 (262)

Hepatotoxicity of Psychotropic Drugs [PDF]

open access: yesHepatology, 1999
Psychotropic drugs with hepatotoxic potential can be classified based on their intended use: 1) antipsychoticsneuroleptics including phenothiazines, butyrophenones, and clozapine; 2) antidepressants including tricyclics, serotonin reuptake inhibitors, and monoamine oxidase (MAO) inhibitors; 3) anti-anxiety drugs such as benzodiazepines; 4 ...
K, Selim, N, Kaplowitz
openaire   +2 more sources

The Slack Channel Deletion Causes Mechanical Pain Hypersensitivity in Mice

open access: yesFrontiers in Molecular Neuroscience, 2022
The role of the Slack (also known as Slo2.2, KNa1.1, or KCNT1) channel in pain-sensing is still in debate on which kind of pain it regulates. In the present study, we found that the Slack–/– mice exhibited decreased mechanical pain threshold but normal ...
Ye Liu   +34 more
doaj   +1 more source

Behaviors Related to Psychiatric Disorders and Pain Perception in C57BL/6J Mice During Different Phases of Estrous Cycle

open access: yesFrontiers in Neuroscience, 2021
Robust sex difference among humans regarding psychiatry- and pain-related behaviors is being researched; however, the use of female mice in preclinical research is relatively rare due to an unchecked potential behavioral variation over the estrous cycle.
Weinan Zhao   +83 more
doaj   +1 more source

The PrLGlu→avBNSTGABA circuit rapidly modulates depression-like behaviors in male mice

open access: yesiScience, 2023
Summary: Depression is a global disease with a high prevalence. Here, we examine the role of the circuit from prelimbic mPFC (PrL) to the anterior ventral bed nucleus of the stria terminalis (avBNST) in depression-like mice through behavioral tests ...
Jie-ying Chen   +5 more
doaj   +1 more source

Protocol to study projection-specific circuits in the basal ganglia of adult mice using viral vector tracing, optogenetics, and patch-clamp technique

open access: yesSTAR Protocols, 2023
Summary: Analysis of synaptic strength and plasticity provides functional insights of complicated neural circuits. Here, we describe steps for cell- and projection-specific optogenetic manipulation of divergent basal ganglia circuits using anterograde ...
Ya-Wei Ji   +4 more
doaj   +1 more source

The Prevalence of Psychotropic Drugs and Relevant Factors in Iranian Youth: A Systematic Review and Meta-Analysis [PDF]

open access: yesAddiction and Health, 2021
Background: Psychotropic drugs can cause many complications and side effects including cognitive, behavioral, and psychological disorders. In recent years, the Iranian youth and adolescents have growingly been using psychotropic drugs.
Ahmad Ali Eslami   +2 more
doaj   +1 more source

Chemical Analysis of Suspected Unrecorded Alcoholic Beverages from the States of São Paulo and Minas Gerais, Brazil

open access: yesJournal of Analytical Methods in Chemistry, 2015
Our study analyzed 152 samples of alcoholic beverages collected from the states of São Paulo and Minas Gerais, Brazil, using gas chromatography with flame ionization detection (GC-FID) and mass spectrometry (GC-MS), Fourier transform infrared ...
Giuseppina Negri   +2 more
doaj   +1 more source

Microglia-derived TNF-α inhibiting GABAergic neurons in the anterior lateral bed nucleus of the stria terminalis precipitates visceral hypersensitivity induced by colorectal distension in rats

open access: yesNeurobiology of Stress, 2022
Irritable bowel syndrome (IBS) is a common and debilitating gastrointestinal disorder that is exacerbated by stress and characterized by abdominal pain.
Ning-Ning Ji   +6 more
doaj   +1 more source

Aberrant expression of FBXO22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice

open access: yesFrontiers in Aging Neuroscience, 2022
Recent observation demonstrated that prolonged anesthesia modifies brain synaptic architecture in all ages, including adult. Propofol is the most commonly utilized anesthetics at clinic.
Xiaoxuan Yang   +16 more
doaj   +1 more source

Psychotropic drugs [PDF]

open access: yesBMJ, 1967
P. Leyburn   +3 more
  +6 more sources

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