Results 31 to 40 of about 9,104 (252)

Pharmacovigilance Signals of the Opioid Epidemic over 10 Years: Data Mining Methods in the Analysis of Pharmacovigilance Datasets Collecting Adverse Drug Reactions (ADRs) Reported to EudraVigilance (EV) and the FDA Adverse Event Reporting System (FAERS)

Pharmaceuticals, 2022
In the past twenty years, the consumption of opioid medications has reached significant proportions, leading to a rise in drug misuse and abuse and increased opioid dependence and related fatalities.
Stefania Chiappini, Rachel Vickers-Smith, Amira Guirguis, John M. Corkery, Giovanni Martinotti, Daniel R. Harris, Fabrizio Schifano   +6 more
doaj   +1 more source

An Expanding World of Novel Psychoactive Substances: Opioids. [PDF]

Front Psychiatry, 2017
The abuse of novel psychoactive substances (NPS) has been increasing dramatically worldwide since late 2000s. By the end of 2015, more than 560 NPS had been reported to the European Monitoring Centre for Drugs and Drug Addiction. Although the most popular compounds are synthetic cannabinoids and psychostimulatory derivatives of cathinone (so-called β ...
Zawilska JB.
europepmc   +5 more sources

Could Hallucinogens Induce Permanent Pupillary Changes in (Ab)users? A Case Report from New Zealand

Case Reports in Neurological Medicine, 2017
An eighteen-year-old female patient of the Caucasian ethnicity from Australasia presented with a persistently dilated pupil causing her discomfort and occasional burning sensation when she is outdoors due to oversensitivity to sunlight.
Ahmed Al-Imam
doaj   +1 more source

Focus on Clozapine Withdrawal- and Misuse-Related Cases as Reported to the European Medicines Agency (EMA) Pharmacovigilance Database

Brain Sciences, 2020
Background: Clozapine is of high clinical relevance for the management of both treatment-resistant schizophrenia and psychotic disturbances with concurrent drug misuse.
Stefania Chiappini, Fabrizio Schifano, John Martin Corkery, Amira Guirguis   +3 more
doaj   +1 more source

The “Endless Trip” among the NPS Users: Psychopathology and Psychopharmacology in the Hallucinogen-Persisting Perception Disorder. A Systematic Review

Frontiers in Psychiatry, 2017
Hallucinogen-persisting perception disorder (HPPD) is a syndrome characterized by prolonged or reoccurring perceptual symptoms, reminiscent of acute hallucinogen effects.
Laura Orsolini, Laura Orsolini, Laura Orsolini, Gabriele Duccio Papanti, Domenico De Berardis, Domenico De Berardis, Domenico De Berardis, Amira Guirguis, John Martin Corkery, Fabrizio Schifano   +9 more
doaj   +1 more source

The Psychonauts’ World of Cognitive Enhancers

Frontiers in Psychiatry, 2020
BackgroundThere is growing availability of novel psychoactive substances (NPS), including cognitive enhancers (CEs) which can be used in the treatment of certain mental health disorders.
Flavia Napoletano, Flavia Napoletano, Fabrizio Schifano, John Martin Corkery, Amira Guirguis, Amira Guirguis, Davide Arillotta, Davide Arillotta, Caroline Zangani, Caroline Zangani, Alessandro Vento, Alessandro Vento, Alessandro Vento   +12 more
doaj   +1 more source

Is There a Risk for Semaglutide Misuse? Focus on the Food and Drug Administration’s FDA Adverse Events Reporting System (FAERS) Pharmacovigilance Dataset

Pharmaceuticals, 2023
Recent media reports commented about a possible issue of the misuse of antidiabetics related to molecules promoted as a weight-loss treatment in non-obese people.
Stefania Chiappini, Rachel Vickers-Smith, Daniel Harris, G. Duccio Papanti Pelletier, John Martin Corkery, Amira Guirguis, Giovanni Martinotti, Stefano L. Sensi, Fabrizio Schifano   +8 more
doaj   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Understanding the Opioid Epidemic through Pharmacovigilance Signals: an Analysis of Pharmacovigilance Datasets collecting Adverse Drug Reactions (ADRs) reported to EudraVigilance (EV) and the FDA Adverse Event Reporting System (FAERS) over 10 Years

Emerging Trends in Drugs, Addictions, and Health
Introduction: In the past twenty years, the consumption of opioid medications has reached significant proportions, leading to the so-called opioid epidemic, characterized by cyclical waves of heroin use and the non-medical use of pharmaceutical opioids ...
S. Chiappini, R. Vickers-Smith, A. Guirguis, J. Corkery, G. Martinotti, D.R. Harris, F. Schifano   +6 more
doaj   +1 more source

The Bridge Between Classical and “Synthetic”/Chemical Psychoses: Towards a Clinical, Psychopathological, and Therapeutic Perspective

Frontiers in Psychiatry, 2019
The critical spread and dissemination of novel psychoactive substances (NPS), particularly among the most vulnerable youngsters, may pose a further concern about the psychotic trajectories related to the intake of new synthetic drugs.
Laura Orsolini, Laura Orsolini, Laura Orsolini, Stefania Chiappini, Duccio Papanti, Domenico De Berardis, Domenico De Berardis, Domenico De Berardis, John M. Corkery, Fabrizio Schifano   +9 more
doaj   +1 more source