Novel psychoactive substances of interest for psychiatry [PDF]
World Psychiatry, 2015 Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives, psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives, phencyclidine-like dissociatives, piperazines, GABA-A/B receptor agonists, a ...
Corkery, John +3 more
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Online surveillance of novel psychoactive substances (NPS): Monitoring Reddit discussions as a predictor of increased NPS-related exposures. [PDF]
Int J Drug Policy, 2021 BACKGROUND Novel psychoactive substances (NPS) present continuous and growing challenges for the scientific, medical, and interventional communities as emerging substances on recreational drug markets change national and international drug landscapes ...
Barenholtz E +10 more
europepmc +4 more sources
Deaths from novel psychoactive substances in England, Wales and Northern Ireland: Evaluating the impact of the UK psychoactive substances act 2016. [PDF]
J Psychopharmacol, 2021 Background: ‘Legal highs’ began appearing in the UK in the mid-2000s. Whilst many of these substances were controlled under the 1971 Misuse of Drugs Act, novel compounds and new variants of controlled compounds were continuously being introduced to the ...
Deen AA +4 more
europepmc +4 more sources
Abuse of Prescription Drugs in the Context of Novel Psychoactive Substances (NPS): A Systematic Review [PDF]
Brain Sciences, 2018 Recently, a range of prescription and over-the-counter drugs have been reportedly used as Novel Psychoactive Substances (NPS), due to their potential for abuse resulting from their high dosage/idiosyncratic methods of self-administration.
Fabrizio Schifano +3 more
doaj +4 more sources
STNGS: a deep scaffold learning-driven generation and screening framework for discovering potential novel psychoactive substances. [PDF]
Brief BioinformThe supervision of novel psychoactive substances (NPSs) is a global problem, and the regulation of NPSs was heavily relied on identifying structural matches in established NPSs databases.
Liu D +13 more
europepmc +2 more sources
Novel psychoactive substances. [PDF]
Br J Gen Pract, 2016 Gilani does well to highlight the increasing and concerning use of novel psychoactive substances (NPS) in the UK.1 We have seen the damaging and unpredictable effects of synthetic cannabinoids in prisons …
Brew I.
europepmc +5 more sources
Development and validation of a rapid LC-MS/MS method for the detection of 182 novel psychoactive substances in whole blood. [PDF]
Drug Test Anal, 2022 Introduction The analysis of novel psychoactive substances (NPS) represents a challenge in forensic toxicology, due to the high number of compounds characterized by different structures and physicochemical properties both among different subclasses and ...
Giorgetti A +6 more
europepmc +2 more sources
"Hot" and "Cold" Cognition in Users of Club Drugs/Novel Psychoactive Substances. [PDF]
Front Psychiatry, 2021 Novel psychoactive substances (NPS) are popular “club/party” drugs that first attracted attention in the UK in 2009 and remained legal until the 2016 Psychoactive Substances Act criminalized their distribution.
Savulich G +6 more
europepmc +2 more sources
Human Neuronal Cell Lines as An In Vitro Toxicological Tool for the Evaluation of Novel Psychoactive Substances. [PDF]
Int J Mol Sci, 2021 Novel psychoactive substances (NPS) are synthetic substances belonging to diverse groups, designed to mimic the effects of scheduled drugs, resulting in altered toxicity and potency.
Sogos V +7 more
europepmc +2 more sources
Molecular mechanisms of action of stimulant novel psychoactive substances that target the high-affinity transporter for dopamine. [PDF]
Neuronal Signal, 2021 Drug misuse is a significant social and public health problem worldwide. Misused substances exert their neurobehavioural effects through changing neural signalling within the brain, many of them leading to substance dependence and addiction in the longer
Sahai MA, Opacka-Juffry J.
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