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The Identification of Drug Abuse. [PDF]
Toxics, 2023 Forensic toxicology has played a central role since its development in defining mechanisms of acute intoxication, often with a lethal outcome [...]
Pieri M.
europepmc +5 more sources
Orphanet Journal of Rare Diseases, 2022 Background Aberrations to endoplasmic/sarcoplasmic reticulum (ER/SR) calcium concentration can result in the departure of endogenous proteins in a phenomenon termed exodosis.
Lacey K. Greer +3 more
doaj +1 more source
Cannabis, medical use and related policies reflections on society (tur)
Klinik Psikiyatri Dergisi, 2020 Cannabis is one of the important food and textile resources that has been used since 4000 BC. The fact that it was used as a medicine by the Chinese caused it to be included in the oldest pharmacopoeia in the world.
Ebru Aldemir +6 more
doaj +1 more source
Nature Communications, 2022 The prefrontal cortex is involved in goal-directed behaviour. Here the authors show that medial prefrontal cortex activates goal-directed motivation and dopamine neurons via a feedback loop with the anteromedial thalamus.
Chen Yang +20 more
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Drug abuse in the Bahamas [PDF]
Journal of Substance Abuse Treatment, 1985 The Bahamas is a group of islands, just off the coast of Florida, extending southwards to near the island of Hispaniola. There are approximately 25 inhabited islands and numerous small islands and cays that are uninhabited. The population of the Bahamas is approximately 230–240,000. A census taken in 1980 showed that approximately 65% of the population
M, Neville, N, Clark
openaire +2 more sources
Prediction of stress and drug craving ninety minutes in the future with passively collected GPS data
npj Digital Medicine, 2020 Just-in-time adaptive interventions (JITAIs), typically smartphone apps, learn to deliver therapeutic content when users need it. The challenge is to “push” content at algorithmically chosen moments without making users trigger it with effortful input ...
David H. Epstein +6 more
doaj +1 more source
A review of implementation research funded by the National Institute on Drug Abuse, 2007-2023: Progress and opportunities. [PDF]
J Subst Use Addict TreatDucharme LJ +4 more
europepmc +3 more sources
Dopamine transients do not act as model-free prediction errors during associative learning
Nature Communications, 2020 Dopamine neurons are proposed to signal the reward prediction error in model-free reinforcement learning algorithms. Here, the authors show that when given during an associative learning task, optogenetic activation of dopamine neurons causes associative,
Melissa J. Sharpe +6 more
doaj +1 more source
Frontiers in Neuroscience, 2015 Methylenedioxypyrovalerone (MDPV) is generally considered to be a more potent cocaine-like psychostimulant, as it shares a similar pharmacological profile with cocaine and induces similar physiological and locomotor responses.
Ken Taro Wakabayashi +2 more
doaj +1 more source
Whole brain dynamics during optogenetic self-stimulation of the medial prefrontal cortex in mice
Communications Biology, 2021 Cover et al. develop a method that permits functional MRI of brain dynamics while mice are cued to perform an operant task: licking a spout to receive optogenetic stimulation to the medial prefrontal cortex.
Christopher G. Cover +6 more
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