Molecular Mechanisms of Action of Novel Psychoactive Substances (NPS). A New Threat for Young Drug Users with Forensic-Toxicological Implications. [PDF]
Life (Basel), 2021 Novel psychoactive substances (NPS) represent a severe health risk for drug users. Even though the phenomenon has been growing since the early 2000s, the mechanisms of action of NPS at the receptors and beyond them are still scarcely understood.
Giorgetti A +7 more
europepmc +2 more sources
Pharmacology of novel psychoactive substances [PDF]
, 2016 This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core +4 more sources
Isomer-Specific Two-Color Double-Resonance IR2MS3 Ion Spectroscopy Using a Single Laser: Application in the Identification of Novel Psychoactive Substances. [PDF]
Anal Chem, 2021 The capability of an ion trap mass spectrometer to store ions for an arbitrary amount of time allows the use of a single infrared (IR) laser to perform two-color double resonance IR–IR spectroscopic experiments on mass-to-charge (m/z) selected ions.
van Geenen FAMG +5 more
europepmc +2 more sources
Sex and Gender Differences in the Effects of Novel Psychoactive Substances. [PDF]
Brain Sci, 2020 Sex and gender deeply affect the subjective effects and pharmaco-toxicological responses to drugs. Men are more likely than women to use almost all types of illicit drugs and to present to emergency departments for serious or fatal intoxications. However,
Fattore L +3 more
europepmc +2 more sources
Understanding the evolving nature of novel psychoactive substances: Mapping 10 years of research
Emerging Trends in Drugs, Addictions, and Health, 2023 Novel psychoactive substances (NPS) is an umbrella term used to describe a heterogeneous group of compounds that mimic the effects of existing drugs and whose demand and use rapidly emerge, change, or even vanish in the drug market.
Alessandro Carollo +4 more
doaj +2 more sources
Analyzing the Open/Deep Web to Better Understand the New/Novel Psychoactive Substances (NPS) Scenarios: Suggestions from CASSANDRA and NPS.Finder Research Projects [PDF]
Brain Sciences, 2020 New/novel psychoactive substances (NPS) are defined as new narcotic/psychotropic drugs which are not controlled by the United Nations’ 1961 Narcotic Drugs/1971 Psychotropic Substances conventions, but which may pose a public health threat [...]
Fabrizio Schifano
doaj +2 more sources
Detecting novel psychoactive substances around the world
Current Opinion in PsychiatryPurpose of review The worldwide spread of novel psychoactive substances (NPS) in the illicit drug market and their continuous increase in number and type, for the purpose of bypassing controlled substance legislation, represents a continuing challenge ...
A. Salomone, Marco Vincenti
semanticscholar +4 more sources
Novel Psychoactive Substances: : the pharmacology of stimulants and hallucinogens [PDF]
Expert Review of Clinical Pharmacology, 2016 This is an Accepted Manuscript of an article published by Taylor & Francis in Expert Review of Clinical Pharmacology, on March 2016, available online at doi: : http://www.tandfonline.com/doi/full/10.1586/17512433.2016.1167597.There are increasing levels ...
Corkery JM +11 more
core +5 more sources
Journal of Chromatography A, 2020 Novel Psychoactive Substances (NPS) represent an alternative to established illicit drugs. They are traded via the internet and exhibit small alterations in their chemical structure to circumvent law, however, their psychotropic effects are comparable ...
M. Schmid, Johannes S. Hägele
semanticscholar +3 more sources
Novel psychoactive substances: What educators need to know. [PDF]
Clin Pharmacol Ther, 2017 Novel psychoactive substances (NPS) are synthetic, psychoactive drugs that are generally not under international regulatory control. NPS are frequently sold as alternatives to classic “street drugs” such as ecstasy or LSD. However, little is known about their pharmacology and toxicity and they therefore pose unknown health risks.
Patterson ZR, Young MM, Vaccarino FJ.
europepmc +4 more sources