Results 21 to 30 of about 9,104 (252)

Identifying New/Emerging Psychoactive Substances at the Time of COVID-19; A Web-Based Approach

Frontiers in Psychiatry, 2021
COVID-19-related disruptions of people and goods' circulation can affect drug markets, especially for new psychoactive substances (NPSs). Drug shortages could cause a change in available NPS, with the introduction of new, unknown, substances. The aims of
Valeria Catalani, Davide Arillotta, John Martin Corkery, Amira Guirguis, Amira Guirguis, Alessandro Vento, Alessandro Vento, Alessandro Vento, Fabrizio Schifano   +8 more
doaj   +1 more source

Novel psychoactive substances and behavioral addictions. [PDF]

Biomed Res Int, 2014
Copyright © 2014 Giovanni Martinotti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Martinotti G, Corazza O, Achab S, Demetrovics Z.   +3 more
europepmc   +9 more sources

COVID-19 Pandemic Impact on Substance Misuse: A Social Media Listening, Mixed Method Analysis

Brain Sciences, 2021
The restrictive measures adopted during the COVID-19 pandemic modified some previously consolidated drug use patterns. A focus on social networks allowed drug users to discuss, share opinions and provide advice during a worldwide emergency context.
Davide Arillotta, Amira Guirguis, John Martin Corkery, Norbert Scherbaum, Fabrizio Schifano   +4 more
doaj   +1 more source

The Psychonauts’ Benzodiazepines; Quantitative Structure-Activity Relationship (QSAR) Analysis and Docking Prediction of Their Biological Activity

Pharmaceuticals, 2021
Designer benzodiazepines (DBZDs) represent a serious health concern and are increasingly reported in polydrug consumption-related fatalities. When new DBZDs are identified, very limited information is available on their pharmacodynamics.
Valeria Catalani, Michelle Botha, John Martin Corkery, Amira Guirguis, Alessandro Vento, Norbert Scherbaum, Fabrizio Schifano   +6 more
doaj   +1 more source

Sex and Gender Differences in the Effects of Novel Psychoactive Substances. [PDF]

Brain Sci, 2020
Sex and gender deeply affect the subjective effects and pharmaco-toxicological responses to drugs. Men are more likely than women to use almost all types of illicit drugs and to present to emergency departments for serious or fatal intoxications. However, women are just as likely as men to develop substance use disorders, and may be more susceptible to
Fattore L, Marti M, Mostallino R, Castelli MP.   +3 more
europepmc   +7 more sources

A Focus on Abuse/Misuse and Withdrawal Issues with Selective Serotonin Reuptake Inhibitors (SSRIs): Analysis of Both the European EMA and the US FAERS Pharmacovigilance Databases

Pharmaceuticals, 2022
Despite increasing reports, antidepressant (AD) misuse and dependence remain underestimated issues, possibly due to limited epidemiological and pharmacovigilance evidence.
Stefania Chiappini, Rachel Vickers-Smith, Amira Guirguis, John Martin Corkery, Giovanni Martinotti, Fabrizio Schifano   +5 more
doaj   +1 more source

Stimulant and hallucinogenic novel psychoactive substances; an update [PDF]

Expert Review of Clinical Pharmacology, 2023
The renewed interest in considering a range of stimulants, psychedelics and dissociatives as therapeutics emphasizes the need to draft an updated overview of these drugs' clinical and pharmacological issues.The focus here was on: stimulants (e.g. amphetamines, methamphetamine, and pseudoephedrine; phenethylamines; synthetic cathinones; benzofurans ...
F, Schifano, A, Vento, N, Scherbaum, A, Guirguis   +3 more
openaire   +3 more sources

Novel psychoactive substances: a novel clinical challenge [PDF]

BMJ Case Reports, 2013
The recreational use of novel psychoactive substances in the UK has increased markedly within the last decade. The variety of new substances synthesised and sold as ‘legal’, often under the pretence of being ‘plant food’ or ‘bath salts’ is similarly increasing. This presents challenges to clinicians: they may be unaware of these substances or unable to
Christopher Daniel, Smith, Margaret, Williams, Maliha, Shaikh   +2 more
openaire   +2 more sources

What about “Pharming”? Issues Regarding the Misuse of Prescription and Over-the-Counter Drugs

Brain Sciences, 2020
Recently, a range of prescription and over-the-counter (OTC) drugs have emerged as being used recreationally, either on their own or in combination with other substances, both licit and illicit, including new psychoactive substances (NPS).
Stefania Chiappini, Fabrizio Schifano
doaj   +1 more source

Genotoxicity Evaluation of The Novel Psychoactive Substance MTTA

International Journal of Molecular Sciences, 2023
MTTA, also known as mephtetramine, is a stimulant novel psychoactive substance characterized by a simil-cathinonic structure. To date, little has been studied on its pharmaco-toxicological profile, and its genotoxic potential has never been assessed. In order to fill this gap, the aim of the present work was to evaluate its genotoxicity on TK6 cells in
Monia Lenzi, Sofia Gasperini, Giorgia Corli, Matteo Marti, Patrizia Hrelia   +4 more
openaire   +3 more sources