Results 11 to 20 of about 6,369 (264)

Cathinone Neurotoxicity (“The “3Ms”) [PDF]

open access: bronzeCurrent Neuropharmacology, 2014
Synthetic cathinones are designer drugs of the phenethylamine class, structurally and pharmacologically similar to amphetamine, 3,4-methylenedioxymethamphetamine (MDMA), cathinone and other related substances. New analogues, legal at least, until formally banned (a time consuming process), are introduced almost daily The United Nations estimates nearly
Steven B. Karch
openalex   +4 more sources

Mephedrone – a synthetic derivative of cathinone

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2023
Novel psychoactive substances (NPS) are a very diverse group of recreational drugs that mimic effects of classic drugs of abuse and, at least at the beginning, are not usually prohibited.
Bielecka-Papierz Gabriela   +2 more
doaj   +3 more sources

Neurotoxicology of Synthetic Cathinone Analogs

open access: hybrid, 2016
The present review briefly explores the neurotoxic properties of methcathinone, mephedrone, methylone, and methylenedioxypyrovalerone (MDPV), four synthetic cathinones most commonly found in "bath salts." Cathinones are β-keto analogs of the commonly abused amphetamines and display pharmacological effects resembling cocaine and amphetamines, but ...
Mariana Angoa‐Pérez   +2 more
openalex   +3 more sources

The clinical challenges of synthetic cathinones [PDF]

open access: bronzeBritish Journal of Clinical Pharmacology, 2019
AimsWithin the new psychoactive substances (NPS) scenario, several hundred different molecules, mostly including synthetic cannabinoids and cathinones, have been identified so far. The aims of the paper were to: (i) identify the number of synthetic cathinones mentioned in a range of psychonaut, NPS‐related, online sources; and (ii) describe the ...
Fabrizio Schifano   +7 more
openalex   +5 more sources

Synthetic cathinone abuse

open access: yesClinical Pharmacology: Advances and Applications, 2013
Michael Capriola Thomasville Medical Center, Thomasville, NC, USA Abstract: The abuse of synthetic cathinones, widely known as bath salts, has been increasing since the mid-2000s.
Capriola M
doaj   +5 more sources

Structure–Activity Relationship of Novel Second-Generation Synthetic Cathinones: Mechanism of Action, Locomotion, Reward, and Immediate-Early Genes

open access: goldFrontiers in Pharmacology, 2021
Several new synthetic cathinones, which mimic the effect of classical psychostimulants such as cocaine or MDMA, have appeared in the global illicit drug market in the last decades.
Nuria Nadal-Gratacós   +16 more
doaj   +2 more sources

Synthetic cathinones related fatalities: an update [PDF]

open access: yesEuropean review for medical and pharmacological sciences, 2018
Synthetic cathinones, more commonly known as "bath salts", are synthetic drugs chemically related to cathinone, a psychostimulant found in the khat plant.
Busardò, F. P.   +5 more
core   +4 more sources

Synthetic Cathinones: Epidemiology, Toxicity, Potential for Abuse, and Current Public Health Perspective

open access: greenBrain Sciences
Synthetic cathinones, derived from cathinone found in the plant Catha edulis, represent the second largest and most frequently seized group of new psychoactive substances.
Shanshan Chen, Wenhua Zhou, Miaojun Lai
doaj   +3 more sources

Brief report: Meth, tranq, gas station heroin & other drugs complicating addiction treatment. [PDF]

open access: yesAm J Addict
Abstract Background and Objectives Patients using fentanyl have worse treatment outcomes; however, little is known about other drugs that complicate treatment. Methods A national survey (n = 396) was conducted using a random sample of clinicians waivered to prescribe buprenorphine in the United States.
Winstanley EL   +5 more
europepmc   +2 more sources

Analytical Challenges in Detecting New Psychoactive Substances in Anti-Doping: A Proof-of-Concept Involving Pentedrone Metabolite. [PDF]

open access: yesDrug Test Anal
The paper describes an investigation related to the pentedrone norephedrine metabolite. The athlete's sample was analyzed using ultra‐performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). According to the literature, this metabolite may originate from pentedrone, α‐pyrrolidinopentiophenone (PVP), or N‐ethylpentedrone (NEP).
Kwiatkowska D   +8 more
europepmc   +2 more sources

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