Results 1 to 10 of about 93,601 (189)

Research Note: Characterization of S-Meq containing the deletion in Meq protein's transactivation domain in a Marek's disease virus strain in Japan

Poultry Science, 2021
: Marek's disease virus (MDV) causes malignant lymphomas in chickens (Marek's disease; MD). Although MD has caused significant economic losses to the poultry industry, currently, its occurrence in the field is effectively controlled by vaccination ...
Tomohiro Okagawa, Shiro Murata, Satoru Konnai   +2 more
exaly   +7 more sources

Characterization of a Very Short Meq Protein Isoform in a Marek’s Disease Virus Strain in Japan

Veterinary Sciences
Marek’s disease virus (MDV) causes malignant lymphoma (Marek’s disease; MD) in chickens. The Meq protein is essential for tumorigenesis since it regulates the expression of host and viral genes.
Tomohiro Okagawa, Shiro Murata, Satoru Konnai   +2 more
exaly   +4 more sources

Marek’s Disease Virus (MDV) Meq Oncoprotein Plays Distinct Roles in Tumor Incidence, Distribution, and Size

Viruses
Marek’s disease (MD), characterized by the rapid onset of T-cell lymphomas in chickens, is caused by Mardivirus gallidalpha2, an oncogenic alphaherpesvirus commonly known as Marek’s disease virus (MDV).
Reddy, Sanjay, Yifei Liao, Blanca Lupiani   +2 more
exaly   +4 more sources

Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence

Viruses, 2022
Marek’s disease virus (MDV) causes malignant lymphoma in chickens (Marek’s disease, MD). Although MD is currently controlled by vaccination, MDV strains have continuously increased in virulence over the recent decades.
Tomohiro Okagawa, Shiro Murata, Satoru Konnai   +2 more
exaly   +3 more sources

Efficient Cross-Screening and Characterization of Monoclonal Antibodies against Marek’s Disease Specific Meq Oncoprotein Using CRISPR/Cas9-Gene-Edited Viruses

Viruses, 2023
Marek’s disease (MD) caused by pathogenic Marek’s disease virus type 1 (MDV−1) is one of the most important neoplastic diseases of poultry. MDV−1-encoded unique Meq protein is the major oncoprotein and the availability of Meq-specific monoclonal ...
Juo Luo, Venugopal Nair, Yongxiu Yao
exaly   +3 more sources

Amino acid insertion in the Meq protein of Marek’s disease virus, an avian oncogenic herpesvirus, accelerates tumorigenesis

Microbiology Spectrum
Marek’s disease virus (MDV) causes lymphomas (Marek’s disease) in chickens. Despite vaccination, MDV field strains exhibit increased virulence, and sporadic outbreaks are still reported.
Tomohiro Okagawa, Shiro Murata, Satoru Konnai   +2 more
exaly   +3 more sources

Genetic evolution of Marek's disease virus in vaccinated poultry farms [PDF]

Veterinary World, 2021
Background and Aim: The Marek's disease virus (MDV) is a neoplastic disease causing serious economic losses in poultry production. This study aimed to investigate MDV occurrence in poultry flocks in the Lower Egypt during the 2020 breakout and ...
Nahed Yehia, Hemat S. El-Sayed, Sabry E. Omar, Ahmed Erfan, Fatma Amer   +4 more
doaj   +1 more source

Bericht über MEQ [Bericht über MEQ]

GMS Zeitschrift für Medizinische Ausbildung, 2007
Hofmann, Marzellus, Scheible, Chi Mi, Zimmermann, Claudia   +2 more
doaj   +1 more source

Fully Attenuated meq and pp38 Double Gene Deletion Mutant Virus Confers Superior Immunological Protection against Highly Virulent Marek’s Disease Virus Infection

Microbiology Spectrum, 2022
Marek’s disease virus (MDV) induces immunosuppression and neoplastic disease in chickens. The virus is controllable via an attenuated meq deletion mutant virus, which has the disadvantage of retaining the ability to induce lymphoid organ atrophy.
Aijun Sun, Xuyang Zhao, Xiaojing Zhu, Zhengjie Kong, Yifei Liao, Man Teng, Yongxiu Yao, Jun Luo, Venugopal Nair, Guoqing Zhuang, Gaiping Zhang   +10 more
doaj   +1 more source

The Influence of Chronotype and Grit on Lifestyle and Physical Activity

Building Healthy Academic Communities Journal, 2020
Background:  The chronotype of a person refers to an individual's natural sleep-wake cycle and whether that individual prefers morning or evening activities, and grit is an individual's perseverance and passion for long-term goals.
Melody F. Allee, Sarah E. Anderson, Myra J. Bloom, Scarlet R. Jost, Donald P. Keating III, Andrew S.I.D. Lang, Nancy V. Mankin, Zachary W. Mast, Philip P. Nelson, Esther M. Spear, Enrique F. Valderrama   +10 more
doaj   +1 more source