Results 1 to 10 of about 74,431 (202)

Research Note: Characterization of S-Meq containing the deletion in Meq protein's transactivation domain in a Marek's disease virus strain in Japan

open access: goldPoultry Science, 2021
: Marek's disease virus (MDV) causes malignant lymphomas in chickens (Marek's disease; MD). Although MD has caused significant economic losses to the poultry industry, currently, its occurrence in the field is effectively controlled by vaccination ...
Tomohiro Okagawa   +2 more
exaly   +7 more sources

Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence [PDF]

open access: goldViruses, 2022
Marek’s disease virus (MDV) causes malignant lymphoma in chickens (Marek’s disease, MD). Although MD is currently controlled by vaccination, MDV strains have continuously increased in virulence over the recent decades.
Tomohiro Okagawa   +2 more
exaly   +4 more sources

Fully Attenuated meq and pp38 Double Gene Deletion Mutant Virus Confers Superior Immunological Protection against Highly Virulent Marek’s Disease Virus Infection

open access: yesMicrobiology Spectrum, 2022
Marek’s disease virus (MDV) induces immunosuppression and neoplastic disease in chickens. The virus is controllable via an attenuated meq deletion mutant virus, which has the disadvantage of retaining the ability to induce lymphoid organ atrophy.
Gaiping Zhang   +2 more
exaly   +3 more sources

Efficient Cross-Screening and Characterization of Monoclonal Antibodies against Marek’s Disease Specific Meq Oncoprotein Using CRISPR/Cas9-Gene-Edited Viruses

open access: yesViruses, 2023
Marek’s disease (MD) caused by pathogenic Marek’s disease virus type 1 (MDV−1) is one of the most important neoplastic diseases of poultry. MDV−1-encoded unique Meq protein is the major oncoprotein and the availability of Meq-specific monoclonal ...
Juo Luo, Venugopal Nair, Yongxiu Yao
exaly   +3 more sources

The prognostic validity of the formative for the summative MEQ (Modified Essay Questions)

open access: yesGMS Journal for Medical Education, 2021
Objective: The purpose of formative examinations is that students and lecturers receive an early feedback regarding the success of learning behavior and teaching methods. These also serve as practice for later summative exams. The aim of this paper is to
Büssing, Oliver   +2 more
doaj   +4 more sources

Characterization of a Very Short Meq Protein Isoform in a Marek’s Disease Virus Strain in Japan

open access: yesVeterinary Sciences
Marek’s disease virus (MDV) causes malignant lymphoma (Marek’s disease; MD) in chickens. The Meq protein is essential for tumorigenesis since it regulates the expression of host and viral genes.
Tomohiro Okagawa   +2 more
exaly   +3 more sources

Validation of the Chinese version of Morningness-Eveningness Questionnaire for screening delayed sleep-wake phase disorder with bipolar disorder among Han Chinese population [PDF]

open access: yesFrontiers in Psychiatry
ObjectiveDelayed sleep-wake phase disorder (DSWPD) is commonly seen in bipolar disorder (BD). However, valid screening tools for DSWPD have not been available, especially in China.
Ting Yang   +3 more
doaj   +2 more sources

Marek’s Disease Virus (MDV) Meq Oncoprotein Plays Distinct Roles in Tumor Incidence, Distribution, and Size

open access: yesViruses
Marek’s disease (MD), characterized by the rapid onset of T-cell lymphomas in chickens, is caused by Mardivirus gallidalpha2, an oncogenic alphaherpesvirus commonly known as Marek’s disease virus (MDV).
Sanjay Reddy   +2 more
exaly   +3 more sources

MEQ Protein #11 : MEQ Anti-Inflammatory Cytokine for Autoimmune Diseases

open access: bronzeJournal of Medical Clinical Case Reports
Amino Acid Sequence: The MEQ Anti-Inflammatory Cytokine is engineered to modulate immune responses, specifically targeting pathways involved in autoimmune diseases. The sequence includes key regions that interact with immune cell receptors to inhibit pro-inflammatory cytokines and promote anti-inflammatory signaling.
openaire   +2 more sources

MEQ Protein #8 MEQ Hormone Analog for Endocrine Disorders

open access: hybridJournal of Diabetes and Endocrinology Research
Amino Acid Sequence: The MEQ Hormone Analog is designed to mimic or modulate the activity of a naturally occurring hormone to treat endocrine disorders. The sequence includes regions that ensure high affinity and specificity for hormone receptors, with modifications to enhance stability and efficacy.
openaire   +2 more sources

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