Results 51 to 60 of about 174,990 (235)

A Genotypic-oriented View of CFTR Genetics Highlights Specific Mutational Patterns Underlying Clinical Macro-categories of Cystic Fibrosis. [PDF]

, 2015
Cystic Fibrosis (CF) is a monogenic disease caused by mutations of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene. The genotype-phenotype relationship in this disease is still unclear, and diagnostic, prognostic and therapeutic ...
Amato, Annalisa, Bertasi, Serenella, Bruno, SABINA MARIA, Cimino, G., Ferraguti, Giampiero, Lucarelli, Marco, Narzi, Fabiana, Pierandrei, Silvia, Quattrucci, Serena, Stamato, Antonella, Strom, Roberto   +10 more
core   +1 more source

Blood Lactate as a Prognostic Biomarker for Survival and Weight Loss in Amyotrophic Lateral Sclerosis: An Exploratory–Validation Study

Annals of Neurology, EarlyView.
Objective Lactate is increasingly recognized as an energy substrate, but its relevance to amyotrophic lateral sclerosis (ALS) remains unclear. We examined whether blood lactate is associated with survival and weight loss in ALS. Methods This retrospective study included an Australian exploratory cohort and a Japanese validation cohort with clinical ...
Ryutaro Nakamura, Frederik J. Steyn, Shuhei Kobashi, Nobuhiro Ogawa, Akihiro Kitamura, Isamu Yamakawa, Robert D. Henderson, Shyuan T. Ngo, Makoto Urushitani   +8 more
wiley   +1 more source

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

Liver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono, Riccardo De Carlis, Alessandro Gambella, Francesca Farnesi, Alice Podestà, Andrea Lauterio, Francesco Tandoi, Luciano De Carlis, Renato Romagnoli   +8 more
wiley   +1 more source

Amino acid insertion in the Meq protein of Marek’s disease virus, an avian oncogenic herpesvirus, accelerates tumorigenesis

Microbiology Spectrum
Marek’s disease virus (MDV) causes lymphomas (Marek’s disease) in chickens. Despite vaccination, MDV field strains exhibit increased virulence, and sporadic outbreaks are still reported.
Jumpei Sato, Shiro Murata, Yoshinosuke Motai, Shwe Yee Win, Hikari Seo, Shunsuke Yamagami, Naoya Maekawa, Tomohiro Okagawa, Satoru Konnai, Kazuhiko Ohashi   +9 more
doaj   +1 more source

Four-fold basal plane anisotropy of the nonlocal magnetization of YNi2B2C [PDF]

, 1999
Studies of single crystal YNi2B2C have revealed a four-fold anisotropy of the equilibrium magnetization in the square crystallographic basal plane. This pi/2 periodicity occurs deep in the superconductive mixed state.
A. Silhanek, A. V. Silhanek, C. V. Tomy, D. J. Singh, D. McK. Paul, D. McK. Paul, J. R. Thompson, K. J. Song, K. J. Song, L. Civale, M. R. Eskildsen, M. Yethiraj, M. Yethiraj, S. Candia, V. G. Kogan, V. G. Kogan, V. G. Kogan, V. Metlushko, Y. De Wilde   +18 more
core   +1 more source

Integrated Assessment of Lipid Oxidation and Off‐Flavor Formation in Plant Protein Powders

Journal of the American Oil Chemists' Society, EarlyView.
Impact of residual lipids on oxylipin and off‐flavor formation in commercial plant proteins: A detailed analysis of precursor‐product relationships by GC‐FID, LC‐MS/MS, and GC‐MS. ABSTRACT The widespread adoption of plant proteins is hindered by their inherent off‐flavors, often linked to lipid oxidation products.
Fernanda Furlan Goncalves Dias, Wellington da Silva Oliveira, Stanislau Bogusz Junior, Ameer Y. Taha   +3 more
wiley   +1 more source

Tradução, equivalência semântica e adaptação cultural do Marijuana Expectancy Questionnaire (MEQ) Translation, semantic equivalence and cultural adaptation of Marijuana Expectancy Questionnaire (MEQ)

Psico-USF, 2004
O objetivo desse estudo foi traduzir, adaptar culturalmente e verificar a equivalência semântica do Marijuana Expectancy Questionnaire (MEQ), o qual avalia as crenças em relação ao uso de maconha, podendo ser importante no tratamento e prognóstico dos ...
Rosemeri Siqueira Pedroso, Margareth da Silva Oliveira, Renata Brasil Araujo, João Feliz Duarte Moraes   +3 more
doaj   +1 more source

High throughput synthesis of 2,5-substituted indoles using a titanium carbenoid bearing boronate functionality [PDF]

, 2008
A titanium benzylidene complex bearing a boronate group converted resin-bound esters into enol ethers. Suzuki cross-coupling with aryl iodides followed by cleavage with acid completed the solid-phase synthesis of 2,5-disubstituted N-Boc-indoles.
Hartley, R.C., Main, C.A., Petersson, H.M., Rahman, S.S.   +3 more
core   +1 more source

A Fast Method for Selecting Bio Sourced Materials of Interest in a Candle Formulation

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT As consumer demand shifts towards more sustainable and nontoxic alternatives, the candle industry is exploring unconventional bio‐based and recycled materials as substitutes for paraffin. Four raw materials, that is rice bran wax (RBW), sugarcane wax (SCW), hydrogenated rapeseed oil (HRO), and waste cooking oil (WCO) were assessed based on ...
Salma Daoufa, Abdellah Arhaliass, Jack Legrand, Delphine Drouin, Raphaëlle Savoire   +4 more
wiley   +1 more source

Urine Tubular Biomarkers Are Associated With Natriuresis in Patients With Acute Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Loop diuretics require functioning kidney tubules to increase the excretion of sodium into urine thereby relieving congestion in patients with acute heart failure (AHF).
Nicholas Wettersten, Stephen Duff, Yu Horiuchi, Dirk J. van Veldhuisen, Sagar Raturi, Michelle M. Estrella, Michael G. Shlipak, Alan Maisel, Patrick T. Murray, Joachim Ix   +9 more
doaj   +1 more source