Results 91 to 100 of about 1,923,232 (348)

Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu   +11 more
wiley   +1 more source

Analysis of Digital Television Signal Reception in Combined Transmitter Antenna Systems

open access: yesJurnal ELTIKOM: Jurnal Teknik Elektro, Teknologi Informasi dan Komputer
The Indonesian broadcasting sector has undergone significant transformation with the implementation of the Analogue Switch Off (ASO) program. By July 2023, approximately 97.23% of television stations in Indonesia had migrated to digital broadcasting ...
Hana Fatimah Zahra   +2 more
doaj   +1 more source

The Seasonal and Inter-Annual Fluctuations of Plankton Abundance and Community Structure in a North Atlantic Marine Protected Area

open access: yesFrontiers in Marine Science, 2019
Marine Protected Areas have become a major tool for the conservation of marine biodiversity and resources. Yet our understanding of their efficacy is often limited because it is measured for a few biological components, typically top predators or species
Fabio Benedetti   +16 more
doaj   +1 more source

A framework for space-efficient string kernels

open access: yes, 2015
String kernels are typically used to compare genome-scale sequences whose length makes alignment impractical, yet their computation is based on data structures that are either space-inefficient, or incur large slowdowns.
A Apostolico   +13 more
core   +1 more source

First Generation Proteolysis Targeting Chimeras (PROTACs) for the Treatment of Progeria

open access: yesAdvanced Science, EarlyView.
We report the first PROTACs designed to degrade progerin, introducing a novel therapeutic approach for progeria. The best compound, UCM‐18142, significantly reduces progerin levels and improves key disease phenotypes in patient‐derived cells and in the LmnaG609G/G609G mouse model, paving the way for new treatment strategies targeting the root cause of ...
Jon Macicior‐Michelena   +5 more
wiley   +1 more source

Dissociative Adsorption: A Solvable Model

open access: yes, 1993
A model of "hot"-dimer deposition in one dimension, introduced by Pereyra and Albano, is modified to have an unbounded dissociation range. The resulting dynamical equations are solved exactly. A related k-mer dissociation model is also introduced and its
Kuzovkov V   +3 more
core   +2 more sources

Scalable Manufacturing of Roll‐to‐Roll Slot‐Die Coated Perovskite Solar Cells

open access: yesAdvanced Science, EarlyView.
Roll‐to‐roll (R2R) slot‐die coating is emerging as a scalable pathway for perovskite solar cells. This mini‐review summarizes advances in ink design, drying control, and electrode integration that enable high‐efficiency flexible devices and modules. Challenges in throughput, stability, and sustainable processing are outlined, guiding the translation of
Farshad Jafarzadeh   +5 more
wiley   +1 more source

Interaction of aluminium hydrolytic species with biomolecules [PDF]

open access: yes, 2008
In this contribution the formation of bioinorganic assemblies between the basic globular protein lysozyme and aqueous aluminium species including Al 13 -mer, Al 30 -mer and colloidal aluminium hydroxide have been explored and comparison made to previous ...
Deschaume, O   +3 more
core  

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

open access: yesAdvanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv   +8 more
wiley   +1 more source

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