Results 71 to 80 of about 1,923,232 (348)

Multidirectional Motion Strategy of Miniature Water Surface Robot Actuated by Single Exciter

Advanced Robotics Research, EarlyView.
A novel multidirectional motion strategy on the water surface based on a single exciter is proposed, and a single‐exciter single‐plate module is developed for actuation. The driving forces generation mechanism of the module is revealed from the perspective of the asymmetric surface wave field.
Haoxuan He, Dehong Wang, Jing Li, Shijing Zhang, Yingxiang Liu   +4 more
wiley   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

RESISTÊNCIA INSTITUCIONAL DO MERCOSUL FRENTE AOS MOVIMENTOS DE RUPTURA DEMOCRÁTICA SUL-AMERICANOS

Revista de Políticas Públicas, 2018
This article aims to discuss the institutional resistance of Mercosur to the ad- vance of conservatism in South America, especially in relation to the post-coup foreign policy of 2016 in Brazil that culminates in the suspension of Venezuela from the bloc
Rogério Santos da Costa
doaj  

Anything Industry Wants: Environmental Policy Under Bush II [PDF]

, 2004
Neuropsykiatriska funktionsnedsättningar är idag lättare att diagnostisera och det är vanligare att barn och ungdomar i skolan vet om att de lever med en diagnos som till exempel Attention deficit hyperactivity disorder (mer känt som ADHD), eller ...
Parenteau, Patrick
core   +1 more source

Parallel approach to sliding window sums

, 2019
Sliding window sums are widely used in bioinformatics applications, including sequence assembly, k-mer generation, hashing and compression. New vector algorithms which utilize the advanced vector extension (AVX) instructions available on modern ...
A Basak, DE Wood, H Li, H Li, I Sović, M Roberts, SF Altschul, TF Smith, V Kotu   +8 more
core   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Sur terre comme sur mer: organisations spatiales en mer du Nord et mer de Norvège [PDF]

, 1998
L'article montre, au moyen de représentations cartographiques et graphiques, les structures spatiales développées en mer pour l'exploitation des hydrocarbures.
Joëlle MAILLARDET, Maryvonne LE BERRE
core   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Microbial Ecotoxicology of Marine Plastic Debris: A Review on Colonization and Biodegradation by the “Plastisphere”

Frontiers in Microbiology, 2019
Over the last decades, it has become clear that plastic pollution presents a global societal and environmental challenge given its increasing presence in the oceans.
Justine Jacquin, Jingguang Cheng, Charlène Odobel, Caroline Pandin, Pascal Conan, Mireille Pujo-Pay, Valérie Barbe, Valérie Barbe, Anne-Leila Meistertzheim, Anne-Leila Meistertzheim, Jean-François Ghiglione   +10 more
doaj   +1 more source

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

Advanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh, Payel Bhanja, Emily Schueddig, Jufri Setianegara, Yuting Lin, Kenny Guida, Shujah Rehman, Stacey Krepel, Devin Koestler, Ronald C. Chen, Katherine L. Cook, Subhrajit Saha   +11 more
wiley   +1 more source