Results 171 to 180 of about 192,759 (291)
Data‐Driven Engineering of Thermostable Collagen‐Mimetic Peptoid Triple Helices
Data‐driven active learning discovery of collagen‐mimetic peptoids capable of forming a thermostable collagen‐like triple helix using computational screening followed by experimental validation. ABSTRACT Collagen‐mimetic peptides (CMPs) are engineered molecules designed to replicate the triple‐helical structure of natural collagen.
Alex Berlaga +6 more
wiley +1 more source
Antibacterial Activity of Estragole From Ocimum tenuiflorum, and Tagetes lucida and Synergistic Effect With Meropenem and Tobramycin Against Multidrug- and Extensively Drug-Resistant (MDR-XDR) Gram-Negative Bacteria. [PDF]
Araque M, Rojas LB.
europepmc +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Fast barcode calling based on <i>k</i>-mer distances. [PDF]
Uphoff RC +3 more
europepmc +1 more source
ABSTRACT Gastric cancer (GC) is the fifth most common type worldwide, representing a public health problem. Among the genes related to this tumorigenesis, the family of matrix metalloproteinases (MMPs), essential regulators of the extracellular matrix (ECM), stand out for their involvement in the development and progression of GC.
Aline Costa Bastos +11 more
wiley +1 more source
GeneMiner2: Accurate and Automated Recovery of Genes From Genome Skimming Data. [PDF]
Yu X +7 more
europepmc +1 more source
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel +5 more
wiley +1 more source
The Advantage of Microelectrode Recording When Pneumocephalus Threatens the Precise Placement of a Deep Brain Stimulator. [PDF]
Walker-Pizarro N +7 more
europepmc +1 more source

