Results 41 to 50 of about 812,587 (357)
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
Environmental Mercury and Its Toxic Effects [PDF]
Journal of Preventive Medicine and Public Health, 2014 Mercury exists naturally and as a man-made contaminant. The release of processed mercury can lead to a progressive increase in the amount of atmospheric mercury, which enters the atmospheric-soil-water distribution cycles where it can remain in ...
Kevin M. Rice +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
Mercury: using the QuPreSS reference model to evaluate predictive services [PDF]
, 2017 Nowadays, lots of service providers offer predictive services that show in advance a condition or occurrence about the future. As a consequence, it becomes necessary for service customers to select the predictive service that best satisfies their needs ...
Bisbal, Jesus +2 more
core +2 more sources
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
Model analyses of atmospheric mercury: present air quality and effects of transpacific transport on the United States [PDF]
Atmospheric Chemistry and Physics, 2013 Atmospheric mercury is a toxic air and water pollutant that is of significant concern because of its effects on human health and ecosystems. A mechanistic representation of the atmospheric mercury cycle is developed for the state-of-the-art global ...
H. Lei +3 more
doaj +1 more source
Mercury in the environment [PDF]
, 1972 Problems in assessing mercury concentrations in environmental materials are discussed. Data for situations involving air, water, rocks, soils, sediments, sludges, fossil fuels, plants, animals, foods, and man are drawn together and briefly evaluated ...
Fulkerson, W. +3 more
core +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Thermogravimetric and distillation studies on mercury, antimony and arsenic sulfides [PDF]
, 1975 Thermogravimetric studies were made on naturally occurring sulfides of mercury, antimony and arsenic to determine activation energies and Arrhenius rates of reaction in vacuum and in atmospheres of air and nitrogen. Of the three sulfides only antimony
Rao, P.D., Town, J.W.
core
Arthritis Care &Research, Accepted Article.Objective This study aimed to determine if program format (in‐person, virtual, hybrid) results in differences in three‐month outcomes of pain, function, quality of life, self‐efficacy and chair stands in a hip/knee osteoarthritis management program. Methods A secondary analysis of the GLA:DTM Canada database was completed.
Jill Van Damme +7 more
wiley +1 more source