Results 221 to 230 of about 104,344 (309)

Wonderings on Agape and Eros: Relationship of Nursing Experience and Values to Liberal Humanism and Posthumanism. [PDF]

Nurs Philos
Valentine SK.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

The effectiveness of virtual reality/motion-sensing games incorporating swing-based elements on upper limb function after stroke: a systematic review and meta-analysis. [PDF]

BMC Neurol
Cai W, Zheng Y, Wu J, Hu G, Takeshita D, Loh PY, He Y.   +6 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

High Enrollment and Representativeness of MACS and WIHS Study Participants in the newly merged MACS/WIHS Combined Cohort Study (MWCCS). [PDF]

AJE Adv
D'Souza G, Herrschaft R, Tien PC, Brown TT, Kassaye SG, Haberlen S, Aouizerat B, Ramirez C, Mimiaga MJ, French AL, Rinaldo CR, Sharma A, Fischl MA, Stosor V, Ofotokun I, Batson J, Holman S, Kempf MC.   +17 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Hospital Mergers, Hospital Choice, and Care Quality for Pregnant Enrollees in Medicaid.

JAMA Health Forum
Desai SM, Padmanabhan P, Glied S, Roberts ET.   +3 more
europepmc   +1 more source

Legume genome structures and histories inferred from Cercis canadensis and Chamaecrista fasciculata genomes. [PDF]

Plant J
Lee HO, Stai JS, Xu Q, Hewavithana T, Soman P, Batra R, Liu A, Jordan BD, Walstead R, Jenkins J, Williams M, Webber J, Grimwood J, Lovell JT, Brůna T, Shu S, Keymanesh K, Eichenberger J, Schmutz J, Goodstein DM, Barry K, Sankoff D, Jin L, Leebens-Mack JH, Cannon SB.   +24 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

1:1 observation and support: a quality improvement approach to reducing cost and improving therapeutic input. [PDF]

BMJ Open Qual
Thomas D, Little M, Pawley J.
europepmc   +1 more source