Results 61 to 70 of about 243,931 (299)
State-owned firms from third countries play an increasingly significant role in international mergers and acquisitions, raising concerns about distortions of competition.
Annika Stöhr, Oliver Budzinski
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
On the Effective Design of the Efficiency Defence [PDF]
The efficiency defence was long delayed in the European merger control due to costly implementation issues. In this paper we argue that the upstream consequences of the efficiency defence should equally be considered, namely the improvement of the ...
Andreea Cosnita, Jean-Philippe Tropeano
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Ex post-merger evaluation: evidence from the Brazilian stock exchange
This paper aims to analyse the (anti)competitive effects of a merger reviewed by the Brazilian competition Authority (CADE): a transaction between BM&FBOVESPA S.A. (BVMF) and CETIP S.A., originating B3 S.A. in 2017.
Lucas Silveira Pordeus +1 more
doaj +1 more source
Research on Market Reaction to JD’s Acquisition of Debon [PDF]
In 2022, JD Logistics acquired a controlling stake in Debon for approximately 9 billion yuan, making it the largest merger and acquisition event in the industry and attracting widespread attention.
Zhang Miansen
doaj +1 more source
Efficiency of EU Merger Control in the 1990-2008 Period [PDF]
The main goal of this paper is to provide an analysis of key regulatory changes in the European merger control and to evaluate their real impact on the efficiency of merger regulation.
Goran Serdarevic, Petr Teply
core +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source

