Results 101 to 110 of about 32,971 (262)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Cross-Border Mergers and acquisitions: Financial and institutional forces [PDF]

open access: yes
Cross-border mergers and acquisitions (M&As) sharply increased over the last two decades. It is often pointed out that cross-border capital reallocation is partly the result of financial liberalization policies, government policies and regional ...
Coeurdacier, Nicolas   +2 more
core  

Trends and regional patterns of cross-border mergers and acquisitions: A case of Malaysian and Indonesian acquirers [PDF]

open access: yes, 2012
Progress of cross-border mergers and acquisitions (M&A) in Asian region demonstrates an upstream pattern although the economy in Europe is unhealthy.In fact, many cross-border deals in Europe are dominated by Asian and US acquirers.In 2010, Asia Pacific
Jedin, Mohd. Haniff
core   +1 more source

CREATING OR DESTROYING VALUE THROUGH MERGERS AND ACQUISITIONS? [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2015
The avalanche of operations performed and their specificities revealed several motivations for mergers and acquisitions However, although they are concluded with the purpose of value creation, reality has shown that in many cases it was exactly the ...
Sehleanu Mariana
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Mergers & Acquisitions research: A bibliometric study of top strategy journals, 2000 - 2009 [PDF]

open access: yes
Mergers and acquisitions (M&As) are important modes through which firms undertake their domestic and international strategies. This bibliometric review examines the extant research on M&As in the top five strategic management journals during a ten years ...
Manuel Portugal Ferreira   +3 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Enemy of Labour? Analysing the Employment Effects of Mergers and Acquisitions [PDF]

open access: yes
This paper analyses the employment effects of mergers and acquisitions by using matched establishment-level data from Finland over the period of 1989-2003. The data covers all sectors.
Böckerman, Petri, Lehto, Eero
core  

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