Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The Valuation Impact of Financial Advisors: An Empirical Analysis of REIT Mergers and Acquisitions [PDF]
This paper analyzes the effect of financial advisor-monitors on the valuation of real estate investment trust (REIT) mergers. Advisor choice determinants and the effect of advisors on transaction value are examined using a sample of REIT mergers for the ...
Richard A. Phillips, Kenneth Daniels
core
Evaluation of Successfulness of Mergers and Acquisitions in the Slovak Republic’s Economic Environment [PDF]
Societas et Iurisprudentia, 2017 Integration of companies is a very difficult process consisting of several phases. The complexity of this process highlights the number of unsuccessful integrations of companies worldwide.
Anna Polednáková
doaj
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Social Network Mixing Patterns in Mergers and Acquisitions-A Simulation Experiment [PDF]
In the contemporary world of global business and continuously growing competition, organizations tend to use mergers and acquisitions to enforce their position on the market.
Robert Fabac +2 more
core
A tentative model of Management Accounting and Control in the Integration Processes of Mergers & Acquisitions [PDF]
, 2005 This article combines the areas of mergers and acquisitions (M&As) and management accounting and control systems (MACS) by developing a tentative model that shows the important variables and how they determine MACS’ involvement in M&A integration ...
Beusch, Peter
core +1 more source
Fractal dimension analysis of stock prices of selected resulting companies after mergers and acquisitions. [PDF]
Eur Phys J Spec Top, 2023 Verma SK, Kumar S.
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Theory and Evidence on Mergers and Acquisitions by Small and Medium Enterprises [PDF]
The theory of mergers and acquisitions (M&As) has been developed almost exclusively from the study of large deals by large firms. In this paper we argue that the behaviour and success of M&As by small and medium sized enterprises (SMEs) may be ...
Killian J McCarthy, Utz Weitzel
core
East-Meets-West: Mergers and Acquisitions challenges and opportunities in and out of Asia. [PDF]
Asian Bus Manag, 2022 Liu Y, Bebenroth R, Yang Y.
europepmc +1 more source