Results 31 to 40 of about 67,694 (293)
Origins of Classic Trigonometric Networks
Kartografija i Geoinformacije, 2009 The paper is a historical overview of beginnings of establishing trigonometric networks to determine the Earth's size and produce accurate maps. First, the book ''Five Books About All Kinds of Triangles'' from 1464 by Johannes Regiomontanus about ...
Miljenko Solarić, Nikola Solarić
doaj
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
针刺研究, 2022 The “meridian” is the core concept of acupuncture medicine. It can be said that almost all the theories and clinical practice of acupuncture and moxibustion in traditional Chinese medicine are based on this concept.
ZHANG Shu-jian, RONG Pei-jing
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Sixty years of meridian-collateral exploration: a road of interdisciplinary research
针刺研究, 2021 The theory of traditional Chinese medicine believes that meridian-collateral(jingluo) is an important system to maintain life and participates in the formation and cure of disease.
SONG Xiao-jing +3 more
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The Effect of Toric Intraocular Lens Implantation in Irregular Corneal Steep and Flat Meridian
Journal of Ophthalmology, 2021 Purpose. To evaluate the effect of toric intraocular lens implantation in cataract patients with irregular corneal steep and flat meridian. Methods.
Ho Sik Hwang +3 more
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PhotonicsThis preliminary study explored circadian variations in meridian-associated skin temperature using infrared thermal imaging (IRTI). Four healthy adults receive a two-hour IRTI measurement alternately over a 24 h period, with thermal images acquired every
Jih-Huah Wu +3 more
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Bile Cast Nephropathy an Important Biliary Culprit of Kidney Injury
Journal of Community Hospital Internal Medicine Perspectives, 2021 Bile cast nephropathy (BCN) is a rare form of acute kidney injury (AKI) that occurs in the setting of hyperbilirubinemia. We present the case of a 67 year-old male with severe kidney injury who was found to have obstructive cholestasis.
Fouzia Yusuf +7 more
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