Results 91 to 100 of about 79,337 (314)

Utility of co-transplanting mesenchymal stem cells in islet transplantation

World Journal of Gastroenterology, 2011
Islet transplantation is characterized by the transplantation of isolated islets from donor pancreata into a diabetic recipient. Although it is a viable choice in the treatment of insulin dependent diabetes mellitus, most patients (approximately 90%) require insulin five years after transplantation.
Gumpei Yoshimatsu, Shinichi Egawa, Naoaki Sakata, Michiaki Unno, Masafumi Goto   +4 more
openaire   +2 more sources

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source

Mesenchymal Stem Cell Insights: Prospects in Hematological Transplantation

Cell Transplantation, 2013
Adult stem cells have been proven to possess tremendous potential in the treatment of hematological disorders, possibly in transplantation. Mesenchymal stem cells (MSCs) are a heterogeneous group of cells in culture, with hypoimmunogenic character to avoid alloreactive T-cell recognition as well as inhibition of T-cell proliferation.
Shiu Huey Chou, Dennis Jine Yuan Hsieh, Chih Yang Huang, Chang Hai Tsai, Shinn Zong Lin, Jing Ying Lin, Cecilia Hsuan Day, Wei Wen Kuo, Fuu Jen Tsai, Chia Yao Shen   +9 more
openaire   +4 more sources

De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties

Advanced Materials, EarlyView.
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang, Jordi Guillem‐Marti, Saurav Kumar, David S. Lee, Daniel Cabrerizo‐Aguado, Rachel Werther, Kevin Alexander Estrada Alamo, Yan Ting Zhao, Adam Nguyen, Irina Kopyeva, Buwei Huang, Jing Li, Yuxin Hao, Xinting Li, Aritza Brizuela‐Velasco, Analisa Murray, Stacey Gerben, Anindya Roy, Cole A. DeForest, Timothy Springer, Hannele Ruohola‐Baker, Jonathan A. Cooper, Melody G. Campbell, Jose Maria Manero, Maria‐Pau Ginebra, David Baker   +25 more
wiley   +1 more source

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

Advanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong, M Sriram, Hepi Hari Susapto, Yixuan Li, Yuan Jiang, Nicolas H. Voelcker, Jennifer L. Young, Andrew W. Holle, Roey Elnathan   +8 more
wiley   +1 more source

The cell repair research of spinal cord injury: a review of cell transplantation to treat spinal cord injury

Journal of Neurorestoratology, 2019
Through retrospective analysis of the literature on the cell repair of spinal cord injury worldwide, it is found that the mechanism of cell transplantation repairing spinal cord injury is mainly to replace damaged neurons, protect host neurons, prevent ...
Zhenrong Zhang, Fangyong Wang, Mingjie Song   +2 more
doaj   +1 more source

Allograftic bone marrow-derived mesenchymal stem cells transplanted into heart infarcted model of rabbit to renovate infarcted heart [PDF]

, 2004
Jianan Wang, Changling Li, Youqi Fan, Hong He, Yong Sun   +4 more
openalex   +1 more source

A biodegradable fibrin scaffold for mesenchymal stem cell transplantation

Biomaterials, 2003
A potential therapy to enhance healing of bone tissue is to deliver isolated mesenchymal stem cells (MSCs) to the site of a lesion to promote bone formation. A key issue within this technology is the development of an injectable system for the delivery of MSCs. Fibrin gel exploits the final stage of the coagulation cascade in which fibrinogen molecules
Bensaïd, W, Triffitt, J, Blanchat, C, Oudina, K, Sedel, L, Petite, H   +5 more
openaire   +4 more sources

Future Frontiers in Bioinspired Implanted Biomaterials

Advanced Materials, EarlyView.
Gu et al. present an integrative overview of cutting‐edge strategies in bioinspired implantable biomaterials for organ regeneration, highlighting how emerging approaches—including 3D bioprinting, scaffold design, hydrogel systems, surface modification, nanofiber engineering, and genetic manipulation—converge to restore structure and function across ...
Qi Gu, Rui Yuan, Dadi Sun, Gordon Wallace   +3 more
wiley   +1 more source

Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium [PDF]

, 2004
Karl‐Henrik Grinnemo, Å Månsson, Göran Dellgren, D Klingberg, Eva Wärdell, Viktor Drvota, Charlotte Tammik, Jan Holgersson, Olle Ringdén, Christer Sylvén, Katarina Le Blanc   +10 more
openalex   +1 more source