Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang +12 more
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GIPC2 regulation of the PKM2/SREBP1 signaling axis controls adipogenic differentiation of mesenchymal stem cells. [PDF]
Wang J +8 more
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Altered lineage commitment of bone marrow mesenchymal stem cells in idiopathic osteonecrosis of the femoral head. [PDF]
Cardín-Pereda A +4 more
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Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of osteoarthritis. [PDF]
Al-Jezani N +11 more
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Application of Machine Learning in Predicting Osteogenic Differentiation of Mesenchymal Stem Cells. [PDF]
Mao H +5 more
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Mesenchymal Stem Cells With Adjuvant Dexamethasone in Patients With Alzheimer's Disease: A Phase IIa Trial. [PDF]
Lee NK +13 more
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Dentinogenic Effect of BMP-7 on Wharton's Jelly Mesenchymal Stem Cells Cultured in Decellularized Dental Pulp. [PDF]
Ahmad Shuhaimi NA +5 more
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It has become clear that adult mammalian bone marrow contains not one but two ostensibly discrete populations of adult stem cells. The first and by far the most fully characterized are the hematopoietic stem cells responsible for maintaining lifelong production of blood cells.
Brenton, Short +4 more
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Mesenchymal Stem Cell Mechanobiology
Current Osteoporosis Reports, 2010Bone marrow-derived multipotent stem and stromal cells (MSCs) are likely candidates for cell-based therapies for various conditions including skeletal disease. Advancement of these therapies will rely on an ability to identify, isolate, manipulate, and deliver stem cells in a safe and effective manner.
Alesha B, Castillo +1 more
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Circulating mesenchymal stem cells
The International Journal of Biochemistry & Cell Biology, 2004Mesenchymal precursor cells (MPCs) are multipotent cells capable of differentiating into various mesenchymal tissues, such as bone, cartilage, fat, tendon and muscle. They are present within both mesenchymal tissues and the bone marrow (BM). If marrow-derived MPCs are to have a role in repair and fibrosis of mesenchymal tissues, transit of these cells ...
C A, Roufosse +3 more
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