Results 31 to 40 of about 1,296,347 (345)

Cannabidiol causes endothelium-dependent vasorelaxation of human mesenteric arteries via CB1 activation

Cardiovascular Research, 2015
Aims The protective effects of cannabidiol (CBD) have been widely shown in preclinical models and have translated into medicines for the treatment of multiple sclerosis and epilepsy.
Christopher P Stanley, William H. Hind, C. Tufarelli, S. O’Sullivan   +3 more
semanticscholar   +1 more source

Inducible nitric oxide synthase-derived superoxide contributes to hypereactivity in small mesenteric arteries from a rat model of chronic heart failure [PDF]

, 2000
The aims of this study were to (a) determine whether inducible nitric oxide synthase (iNOS) is expressed in small mesenteric arteries from rats with chronic heart failure (CHF), (b) investigate the functional significance of this potential source of ...
Gray, G A, Megson, I L, Miller, A A
core   +2 more sources

Reduced activity of SKCa and Na-K ATPase underlies the accelerated impairment of EDH-type relaxations in mesenteric arteries of aging spontaneously hypertensive rats

Pharmacology Research & Perspectives, 2015
Aging is accompanied by endothelial dysfunction due to reduced bioavailability of nitric oxide (NO) and/or reduced endothelium‐dependent hyperpolarizations (EDH).
B. Kong, R. Man, Yuansheng Gao, P. Vanhoutte, S. Leung   +4 more
semanticscholar   +1 more source

α1D-Adrenoceptors are responsible for the high sensitivity and the slow time-course of noradrenaline-mediated contraction in conductance arteries [PDF]

, 2013
The objective of this study was to determine whether the different time-course characteristics of α1-adrenoceptor-mediated contraction in arteries can be related to the subtypes involved.
Alexander, Arévalo-León, Cavalli, Chalothorn, Chen, Cotecchia, Daly, Deighan, Docherty, García-Cazarín, García-Sainz, García-Sainz, García-Sainz, Gisbert, Gisbert, Gisbert, Gisbert, Goldstein, Hawrylyshyn, Hein, Hosoda, Hrometz, Hussain, Keffel, Kenny, Koshimizu, Lachnit, Lyssand, Lyssand, Lyssand, Martinez-Rivelles, Martí, McCune, Methven, Methven, Michelotti, Monto, Noguera, Noguera, Philipp, Piascik, Piascik, Pérez-Aso, Rudner, Schwinn, Stassen, Taguchi, Tanaka, Tanoue, Tanoue, Theroux, Yamamoto, Zhong, Ziani   +53 more
core   +1 more source

Superior Mesenteric Artery Embolectomy*

Annals of Surgery, 1964
GANGRENE of the small bowel and ascending colon commonly follows occlusion of the superior mesenteric artery. Such intestinal necrosis is preventable by early arterial reconstructive surgery, but diagnosis of mesenteric occlusion is notoriously difficult.
G D, ZUIDEMA, D, REED, J G, TURCOTTE, W J, FRY   +3 more
openaire   +5 more sources

Sex‐specific alterations in NOS regulation of vascular function in aorta and mesenteric arteries from spontaneously hypertensive rats compared to Wistar Kyoto rats

Physiological Reports, 2014
The present study tested the hypothesis that spontaneously hypertensive rats (SHR) have impaired nitric oxide synthase (NOS)‐mediated regulation of vascular function versus Wistar‐Kyoto rats (WKY).
A. Loria, Krystal N. Brinson, Brandon M. Fox, J. Sullivan   +3 more
semanticscholar   +1 more source

Spinal cord injury increases the reactivity of rat tail artery to angiotensin II

Frontiers in Neuroscience, 2015
Studies in individuals with spinal cord injury (SCI) suggest the vasculature is hyperreactive to angiotensin II (Ang II). In the present study, the effects of SCI on the reactivity of the rat tail and mesenteric arteries to Ang II have been investigated.
Hussain eAl Dera, Hussain eAl Dera, James Alexander Brock   +2 more
doaj   +1 more source

Deletion of murine slc29a4 modifies vascular responses to adenosine and 5‐hydroxytryptamine in a sexually dimorphic manner

Physiological Reports, 2020
Equilibrative nucleoside transporter 4 (ENT4), encoded by SLC29A4, mediates the flux of both 5‐hydroxytryptamine (5‐HT) and adenosine across cell membranes.
Ran Wei, Stephen L. Gust, David Tandio, Alexia Maheux, Khanh H. Nguyen, Joanne Wang, Stephane Bourque, Frances Plane, James R. Hammond   +8 more
doaj   +1 more source

Role of Cholesterol in the Regulation of Hydrogen Sulfide Signaling within the Vascular Endothelium

Antioxidants, 2022
H2S is a gaseous signaling molecule enzymatically produced in mammals and H2S-producing enzymes are expressed throughout the vascular wall. We previously reported that H2S-induced vasodilation is mediated through transient receptor potential cation ...
Perenkita J. Mendiola, Emily E. Morin, Laura V. Gonzalez Bosc, Jay S. Naik, Nancy L. Kanagy   +4 more
doaj   +1 more source

Effects of Methotrexate on IL-6alphar, VCAM-1 and NF Kappa B Expression in a Rat Model of Metabolic Syndrome [PDF]

, 2016
Background: In this study, we used Methotrexate (Mtx) to examine the role of immunomodulation on the activation of IL-6 and VCAM-1, which could generate a microenvironment that supports cardiovascular remodelling.Methods: Male WKY and SHR rats were ...
Diez, Emiliano Raúl, García, Rodrigo Damián, Miatello, Roberto Miguel, Ramirez, Jésica M., Renna, Nicolas Federico   +4 more
core   +1 more source