A Vasoactive Role for Endogenous Relaxin in Mesenteric Arteries of Male Mice [PDF]
PLoS ONE, 2014 The peptide hormone relaxin has striking effects on the vascular system. Specifically, endogenous relaxin treatment reduces myogenic reactivity through nitric oxide (NO)-mediated vasorelaxation and increases arterial compliance in small resistance ...
Chen Huei Leo +2 more
exaly +4 more sources
AdipoRon, adiponectin receptor agonist, improves vascular function in the mesenteric arteries of type 2 diabetic mice. [PDF]
PLoS ONE, 2020 BACKGROUND:An orally active synthetic adiponectin receptor agonist, AdipoRon has been suggested to ameliorate insulin resistance, and glucose tolerance.
Soo-Kyoung Choi +4 more
doaj +3 more sources
Dapagliflozin induces vasodilation in resistance-size mesenteric arteries by stimulating smooth muscle cell KV7 ion channels [PDF]
Heliyon, 2022 Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that, in addition to glucose reduction, lowers systemic blood pressure. Here, we investigated if dapagliflozin could directly relax small mesenteric arteries that control peripheral ...
Ahasanul Hasan +3 more
doaj +2 more sources
ET-CORM Mediated Vasorelaxation of Small Mesenteric Arteries: Involvement of Kv7 Potassium Channels [PDF]
Frontiers in Pharmacology, 2021 Although the vasoactive properties of carbon monoxide (CO) have been extensively studied, the mechanism by which CO mediates vasodilation is not completely understood.
Danfeng Zhang +8 more
doaj +2 more sources
Coupling of store-operated calcium entry to vasoconstriction is acid-sensing ion channel 1a dependent in pulmonary but not mesenteric arteries. [PDF]
PLoS ONE, 2020 Although voltage-gated Ca2+ channels (VGCC) are a major Ca2+ entry pathway in vascular smooth muscle cells (VSMCs), several other Ca2+-influx mechanisms exist and play important roles in vasoreactivity.
Selina M Garcia +4 more
doaj +2 more sources
Vasodilatory Effect of Alpinia officinarum Extract in Rat Mesenteric Arteries. [PDF]
Molecules, 2022 Background: Alpinia officinarum (A. officinarum) is known to exhibit a beneficial effect for anti-inflammatory, anti-oxidant, and anti-hyperlipidemic effects.
Haam CE +5 more
europepmc +2 more sources
Clinical and Experimental Hypertension, 2023 Objective Endothelial dysfunction is a critical initiating factor in the development of hypertension and related complications. Follistatin-like 1 (FSTL1) can promote endothelial cell function and stimulates revascularization in response to ischemic ...
Hanwen Liu +6 more
doaj +1 more source
Sphingosine-1-Phosphate Signaling Regulates Myogenic Responsiveness in Human Resistance Arteries. [PDF]
PLoS ONE, 2015 We recently identified sphingosine-1-phosphate (S1P) signaling and the cystic fibrosis transmembrane conductance regulator (CFTR) as prominent regulators of myogenic responsiveness in rodent resistance arteries.
Sonya Hui +10 more
doaj +1 more source
Jornal Vascular Brasileiro, 2023 The renal arteries arise from the lateral side of the abdominal aorta at the L2 vertebral level, just below the origin of the superior mesenteric artery.
Naveen Kumar +3 more
doaj +1 more source
Frontiers in Physiology, 2022 Aim: TASK-1 channels are established regulators of pulmonary artery tone but their contribution to the regulation of vascular tone in systemic arteries is poorly understood.
Anastasia A. Shvetsova +4 more
doaj +1 more source