Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries [PDF]
, 2017 Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial ...
Broekelmann, Thomas J +5 more
core +3 more sources
Bilateral Multiple Renal Vessels: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2014 The kidneys receive arterial supply from the paired renal arteries. During routine dissection we observed in an adult male cadaver the following variation. Bilateral variation is seen in 5%-10% of individuals.
Sulabha Hanumant Deshpande +2 more
doaj +1 more source
Mitochondrial regulation of NADPH oxidase in hindlimb unweighting rat cerebral arteries.
PLoS ONE, 2014 Exposure to microgravity results in post-flight cardiovascular deconditioning and orthostatic intolerance in astronauts. Vascular oxidative stress injury and mitochondrial dysfunction have been indicated in this process.
Ran Zhang +8 more
doaj +1 more source
Journal of Pharmacological Sciences, 2016 The present study investigated pharmacological characterizations of muscarinic acetylcholine receptor (AChR) subtypes involving ACh-induced endothelium-independent vasodilatation in rat mesenteric arteries.
P. Tangsucharit +6 more
semanticscholar +1 more source
c-Src inhibition improves cardiovascular function but not remodeling or fibrosis in Ang II-induced hypertension [PDF]
, 2016 c-Src plays an important role in angiotensin II (Ang II) signaling. Whether this member of the Src family kinases is involved in the development of Ang II–induced hypertension and associated cardiovascular damage in vivo remains unknown. Here, we studied
Antunes, Tayze T. +6 more
core +1 more source
Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: the aldosterone-mineralocorticoid receptor-Nox1 Axis [PDF]
, 2017 Aims: We questioned whether aldosterone and oxidative stress play a role in vascular damage in severe hypertension and investigated the role of Nox1 in this process.
Ceravolo, Graziela +7 more
core +1 more source
Cardiovascular Research, 2015 Aims The protective effects of cannabidiol (CBD) have been widely shown in preclinical models and have translated into medicines for the treatment of multiple sclerosis and epilepsy.
Christopher P Stanley +3 more
semanticscholar +1 more source
Superior Mesenteric Artery Embolectomy*
Annals of Surgery, 1964 GANGRENE of the small bowel and ascending colon commonly follows occlusion of the superior mesenteric artery. Such intestinal necrosis is preventable by early arterial reconstructive surgery, but diagnosis of mesenteric occlusion is notoriously difficult.
G D, ZUIDEMA +3 more
openaire +5 more sources
α1D-Adrenoceptors are responsible for the high sensitivity and the slow time-course of noradrenaline-mediated contraction in conductance arteries [PDF]
, 2013 The objective of this study was to determine whether the different time-course characteristics of α1-adrenoceptor-mediated contraction in arteries can be related to the subtypes involved.
Alexander +53 more
core +1 more source
Effects of Methotrexate on IL-6alphar, VCAM-1 and NF Kappa B Expression in a Rat Model of Metabolic Syndrome [PDF]
, 2016 Background: In this study, we used Methotrexate (Mtx) to examine the role of immunomodulation on the activation of IL-6 and VCAM-1, which could generate a microenvironment that supports cardiovascular remodelling.Methods: Male WKY and SHR rats were ...
Diez, Emiliano Raúl +4 more
core +1 more source