Results 131 to 140 of about 35,794 (250)

Contractive function of mesenteric lymph nodes in obese rats

Problems of Nutrition
Over the past 50 years, the prevalence of obesity around the world has increased several times and has become a pandemic. The effect of obesity on the lymphatic system, which plays a key role in the regulation of fluid homeostasis, immune cell migration, antigen presentation, and resolution of inflammatory responses, is poorly understood, and there is ...
openaire   +2 more sources

Advances in the treatment of systemic lupus erythematosus: Biologicals, small‐molecular agents, and cell‐depleting therapies coming to the clinic

Journal of Internal Medicine, Volume 300, Issue 4, Page 461-479, October 2026.
Abstract Systemic lupus erythematosus (SLE; lupus) remains a particular challenge for the practicing clinician on account of its chronic undulating and unpredictable course, its diverse manifestations, and—until recently—limited treatment options all associated with considerable downsides.
Ronald van Vollenhoven
wiley   +1 more source

Genotype II Live‐Attenuated ASFV Vaccine Bearing 24 Genes Deletion in 3 Independent Regions Is Able to Provide Complete Protection Against Homologous Lethal Challenge

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
African swine fever (ASF) is a highly contagious and lethal viral disease of swine. Therefore, it is urgent to develop a safe and effective vaccine. We constructed a live‐attenuated ASF vaccine bearing 24 gene deletions in 3 independent regions, ASFV‐Δ24.
Fan Xu, Wen Dang, Yu Du, Tao Li, Huanan Liu, Zhengwang Shi, Hong Tian, Jijun He, Haixue Zheng   +8 more
wiley   +1 more source

Cavitating mesenteric lymph node syndrome: a rare complication of celiac disease-case report and literature review. [PDF]

Oxf Med Case Reports
Aaboudech TY, Derqaoui S, Mesmoudi S, Cherkaoui M, Jahid A, Errabih I, Bernoussi Z, Znati K.   +7 more
europepmc   +1 more source

Real‐world clinical impact of implementing and updating a deep learning‐based automatic contouring system in rectal cancer radiotherapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 9, September 2026.
Abstract Background Accurate delineation of target volumes and organs‐at‐risk (OARs) is a critical yet labor‐intensive component of rectal cancer radiotherapy. While deep learning (DL)‐based automatic contouring systems are increasingly used to address inter‐observer variability and improve efficiency, artificial intelligence models require rigorous ...
Ningyu Wang, Tongzhen Xu, Yujie Kang, Yuting Liang, Wenyu Wang, Wensheng Nie, Jianrong Dai, Yuan Tang, Kuo Men   +8 more
wiley   +1 more source

Curatively Resected Mesenteric Lymph Node Recurrence of Ewing Sarcoma. [PDF]

Surg Case Rep
Tachikawa A, Kawai K, Dejima A, Nakamori S, Kato H, Natsume S, Takao M, Shiratori H, Nakano D, Motoi T, Hirai T.   +10 more
europepmc   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, Volume 13, Issue 49, 3 September 2026.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

Advanced Science, Volume 13, Issue 52, 18 September 2026.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun, He Li, Xu Zhu, Zijian Zhang, Deshan Ren, Shuai Ding, Yan Li   +6 more
wiley   +1 more source

Cavitating Mesenteric Lymph Node Syndrome With Autoimmune Pancreatitis and Hepatitis: A Case Report and Literature Review. [PDF]

Cureus
Chama A, Saliba W, Nasr A.
europepmc   +1 more source

WT1‐Targeted Oral Bifidobacterium longum Vaccine Enhances Checkpoint Blockade Efficacy in Pancreatic Cancer

Advanced Science, Volume 13, Issue 54, 28 September 2026.
Oral WT1‐targeted Bifidobacterium longum vaccine promotes WT1‐associated cellular immunity and enhances anti‐PD‐1/anti‐CTLA‐4 efficacy in pancreatic cancer. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains largely unresponsive to immune checkpoint inhibitors (ICI) due to its profoundly immunosuppressive tumor microenvironment.
Taiki Yamazaki, Aori Minami, Misako Hirota, Mirei Hirano, Ryota Sato, Atsuki Honma, Hideto Ueki, Toshiro Shirakawa   +7 more
wiley   +1 more source