Results 71 to 80 of about 178,332 (312)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Multi-Size-Mesh, Multi-Time-Step Algorithm for Noise Computation on Curvilinear Meshes [PDF]

open access: yes, 2013
Aeroacoustic problems are often multi-scale and a zonal refinement technique is thus desirable to reduce computational effort while preserving low dissipation and low dispersion errors from the numerical scheme.
CORRE, Christophe   +3 more
core   +1 more source

WingMesh: A Matlab-Based Application for Finite Element Modeling of Insect Wings

open access: yesInsects, 2020
The finite element (FE) method is one of the most widely used numerical techniques for the simulation of the mechanical behavior of engineering and biological objects.
Shahab Eshghi   +4 more
doaj   +1 more source

Adaptive Physics-Based Non-Rigid Registration for Immersive Image-Guided Neuronavigation Systems

open access: yesFrontiers in Digital Health, 2021
Objective: In image-guided neurosurgery, co-registered preoperative anatomical, functional, and diffusion tensor imaging can be used to facilitate a safe resection of brain tumors in eloquent areas of the brain. However, the brain deforms during surgery,
Fotis Drakopoulos   +15 more
doaj   +1 more source

Learned Adaptive Mesh Generation

open access: yesCoRR
Elliptic Partial Differential Equations (PDEs) play a central role in computing the equilibrium conditions of physical problems (heat, gravitation, electrostatics, etc.). Efficient solutions to elliptic PDEs are also relevant to computer graphics since they encode global smoothness with local control leading to stable, well-behaved solutions.
Zhang, Zhiyuan   +3 more
openaire   +3 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Fast Adaptive Quadtree Mesh Generation [PDF]

open access: yes, 1998
International audienceA size-governed quadtree mesh generation method is presented in this paper to deal with planar domains of arbitrary shape. The tree decomposition provides a convenient control space, which can be used to determine the element sizes,
Maréchal, Loïc, Frey, Pascal
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

ITEM: Inter-Texture Error Measurement for 3D Meshes [PDF]

open access: yes, 2011
We introduce a simple and innovative method to compare any two texture maps, regardless of their sizes, aspect ratios, or even masks, as long as they are both meant to be mapped onto the same 3D mesh.
Rafael Pagés   +5 more
core   +2 more sources

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