Results 71 to 80 of about 579,579 (293)
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Dynamic on-mesh procedural generation
, 2015 We present a method to synthesize procedural models with global structures, such as growth plants, on existing surfaces at interactive time. More generally, our approach extends shape grammars to enable context-sensitive procedural generation on the GPU. Central to our framework is the unified representation of external contexts as texture maps.
Buron, Cyprien +3 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Examples of finite element mesh generation using SDRC IDEAS [PDF]
, 1990 IDEAS (Integrated Design Engineering Analysis Software) offers a comprehensive package for mechanical design engineers. Due to its multifaceted capabilities, however, it can be manipulated to serve the needs of electrical engineers, also.
Volakis, John L., Zapp, John
core +1 more source
Phase-field modeling of brittle fracture with multi-level hp-FEM and the finite cell method
, 2018 The difficulties in dealing with discontinuities related to a sharp crack are overcome in the phase-field approach for fracture by modeling the crack as a diffusive object being described by a continuous field having high gradients.
Ambati, Marreddy +5 more
core +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Engineering ReportsIn this article, we integrate the template method and the mapping method to propose a new approach for generating quadrilateral meshes with controllable density transitions for planar geometric models.
Yize Li, Qingyuan Hu, Gengdong Cheng
doaj +1 more source
The use of the mesh free methods (radial basis functions) in the modeling of radionuclide migration and moving boundary value problems [PDF]
, 2007 Recently, the mesh free methods (radial basis functions-RBFs) have emerged as a novel computing method in the scientific and engineering computing community.
Runovc, Franc +2 more
core
, 2010 Heterogeneous anisotropic diffusion problems arise in the various areas of science and engineering including plasma physics, petroleum engineering, and image processing.
Aavatsmark +65 more
core +1 more source