Results 61 to 70 of about 178,332 (312)

Polygonal finite element-based content-aware image warping

open access: yesComputational Visual Media, 2023
Mesh-based image warping techniques typically represent image deformation using linear functions on triangular meshes or bilinear functions on rectangular meshes. This enables simple and efficient implementation, but in turn, restricts the representation
Juan Cao   +3 more
doaj   +1 more source

Designing Parallel Adaptive Laplacian Smoothing for Improving Tetrahedral Mesh Quality on the GPU

open access: yesApplied Sciences, 2021
Mesh quality is a critical issue in numerical computing because it directly impacts both computational efficiency and accuracy. Tetrahedral meshes are widely used in various engineering and science applications.
Ning Xi, Yingjie Sun, Lei Xiao, Gang Mei
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The Adaptive Composite Block-Structured Grid Calculation of the Gas-Dynamic Characteristics of an Aircraft Moving in a Gas Environment

open access: yesMathematics, 2022
This paper considers the problem associated with the numerical simulation of the interaction between the cocurrent stream occurring near a monoblock moving in the gas medium and solid fuel combustion products flowing from a solid fuel rocket engine (SFRE)
Victor V. Kuzenov   +2 more
doaj   +1 more source

Generative Mesh Modeling

open access: yes, 2005
Die generative Modellierung ist ein alternativer Ansatz zur Beschreibung von dreidimensionaler Form. Zugrunde liegt die Idee, ein Modell nicht wie üblich durch eine Ansammlung geometrischer Primitive (Dreiecke, Punkte, NURBS-Patches) zu beschreiben, sondern durch Funktionen.
openaire   +3 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

A Level Set-Based Actuator Disc Model for Turbine Realignment in Wind Farm Simulation: Meshing, Convergence and Applications

open access: yesEnergies, 2022
We present a novel meshing and simulation approach for wind farms, featuring realignment and mesh adaptation. The turbines are modeled with actuator discs, which are discretized by means of an adaptation process to represent a level set function.
Abel Gargallo-Peiró   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

POD-Kriging Reduced Method's Application in Tandem Cylinders' Flow [PDF]

open access: yesXibei Gongye Daxue Xuebao, 2018
The configuration of Tandem Cylinders is a typical one in researching noise and interactions between different components, where the distance-diameter ratio is a very significant parameter with which the flow form varies a lot.

doaj   +1 more source

The Generation of Valid Curvilinear Meshes [PDF]

open access: yes, 2015
It is now well-known that a curvilinear discretization of the geometry is most often required to benefit from the computational efficiency of high-order numerical schemes in simulations. In this article, we explain how appropriate curvilinear meshes can be generated.
Geuzaine, Christophe   +4 more
openaire   +2 more sources

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