Results 61 to 70 of about 3,054,654 (282)
The Generation of Valid Curvilinear Meshes [PDF]
, 2015 It is now well-known that a curvilinear discretization of the geometry is most often required to benefit from the computational efficiency of high-order numerical schemes in simulations. In this article, we explain how appropriate curvilinear meshes can be generated.
Geuzaine, Christophe +4 more
openaire +2 more sources
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
A Clustering-Based Bubble Method for Generating High-Quality Tetrahedral Meshes of Geological Models
Applied Sciences, 2020 High-quality mesh generation is critical in the finite element analysis of displacements and stabilities of geological bodies. In this paper, we propose a clustering-based bubble method for generating high-quality tetrahedral meshes of geological models.
Bowen Wang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Shelling Hexahedral Complexes for Mesh Generation
Journal of Graph Algorithms and Applications, 2001 We present a new approach for the generation of hexahedral finite element meshes for solid bodies in computer-aided design. The key idea is to use a purely combinatorial method, namely a shelling process, to decompose a topological ball with a ...
Matthias Müller-Hannemann
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Learned Adaptive Mesh Generation
CoRRElliptic Partial Differential Equations (PDEs) play a central role in computing the equilibrium conditions of physical problems (heat, gravitation, electrostatics, etc.). Efficient solutions to elliptic PDEs are also relevant to computer graphics since they encode global smoothness with local control leading to stable, well-behaved solutions.
Zhang, Zhiyuan +3 more
openaire +4 more sources
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
FastM: Design and Evaluation of a Fast Mobility Mechanism for Wireless Mesh Networks [PDF]
, 2009 Although there is a large volume of work in the literature in terms of mobility approaches for Wireless Mesh Networks, usually these approaches introduce high latency in the handover process and do not support realtime services and applications. Moreover,
Couto, Luís +3 more
core
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source