Results 31 to 40 of about 27,088 (253)
Mesh shape-quality optimization using the inverse mean-ratio metric [PDF]
Mathematical Programming, 2006 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Subdivision Strategies for Bone Models: A Comprehensive Analysis of Geometric and Visual Quality
IEEE AccessBone fracture modeling is a major challenge in medical image analysis and simulation, requiring accurate strategies to faithfully represent complex fracture patterns.
G. Parra-Cabrera +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Simplification of locally refined gradient meshes
Graphical ModelsGradient meshes are powerful vector graphic primitives known for producing smooth and detailed color transitions. However, their fixed rectangular topology complicates editing, as adding detail in one region introduces control points across the entire ...
E. Kato +3 more
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Comparison of Noise Reduction Algorithms for Optical Coherence Tomography Images of Skin Melanoma
Известия высших учебных заведений России: Радиоэлектроника, 2020 Introduction. Optical coherence tomography (ОКТ) is a non-invasive instrument for studying optically heterogeneous media with micron precision, including skin cancer. However, ОКТ tissue images are very noisy.
O. O. Myakinin
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Tumor Treating Fields for Ovarian Carcinoma: A Modeling Study
Advances in Radiation Oncology, 2021 Purpose: Since the inception of tumor treating fields (TTFields) therapy as a Food and Drug Administration–approved treatment with known clinical efficacy against recurrent and newly diagnosed glioblastoma, various in silico modeling studies have been ...
Edwin Lok, MS +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
METRICS FOR IMAGE SURFACE APPROXIMATION BASED ON TRIANGULAR MESHES
Image Analysis and Stereology, 2018 Surface approximation plays an important role in several application fields, such as computer-aided design, computer graphics, remote sensing, computer vision, robotics, architecture, and manufacturing.
Eduardo Sant'Ana da Silva +2 more
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