A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg +16 more
wiley +1 more source
Topology Optimization of High-Performance Optomechanical Resonator. [PDF]
Shi Y +4 more
europepmc +1 more source
A bio‐inspired bidirectional‐winding origami platform enables scalable and programmable deployable structures. Double axial folding inspired by earwig hindwings and Flasher‐based hybridization create modular multilayer architectures with diverse attainable winding angles under fixed boundary conditions.
Wenyao Zhang +5 more
wiley +1 more source
Experimental and Numerical Study on Various Liquid-Cooled Heat Sinks Including Topology Optimization. [PDF]
Shi G +7 more
europepmc +1 more source
A bio‐inspired side‐chain branching strategy is developed to orchestrate a dual noncovalent conformational locking (NoCL) network, enabling the construction of perfectly planar NIR‐II phototheranostic aggregates. Such structural precision maximizes light‐harvesting efficiency and optimizes exciton dynamics, ensuring synchronized enhancements in NIR‐II ...
Cheng Lu +11 more
wiley +1 more source
Bionic optimization design of bed for high-precision turn-milling compound machine tool based on the honeycomb structure. [PDF]
Bing X +5 more
europepmc +1 more source
A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source
A Clinically Compatible Method for Generating Preoperative Finite Element Models to Simulate Facial Appearance and Movements in Orthognathic Surgery. [PDF]
Picard MC +6 more
europepmc +1 more source
Surface and Interfacial Engineering toward Durable Mechanically Coupled Flexible Electronics
This Review highlights how surface and interfacial engineering governs the reliability, durability, and functional stability of mechanically coupled flexible electronics. By integrating fundamental interfacial theory, failure mechanisms, multiscale engineering strategies, and representative applications, it provides a design‐oriented framework for ...
Qian Wang, Fangfang Dai, Wei Wu
wiley +1 more source
Fabrication of graphene-based quantum Hall networks and influences of partial star-mesh recursion. [PDF]
Scaletta DS +9 more
europepmc +1 more source

