A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source
Stress Field Prediction and DIC-Informed Spatial Regularization for AlSi10Mg Alloy Tensile Specimens Based on Graph Neural Networks. [PDF]
Dong Z, Xie X, Yang G, Li Z, Li X, Ma H.
europepmc +1 more source
Geometric constraint reconfiguration enables a rigid–foldable kirigami‐inspired mechanism to switch between twisting, directional translation, and self‐locking states. By encoding multifunctionality directly into its architecture, the mechanism achieves multimodal motion and passive locking without reassembly, providing a compact platform for adaptive ...
Jianlin Wang, Zhongmin Song, Ketao Zhang
wiley +1 more source
A manufacturability-informed topology framework for AI-guided design of fibrous network materials. [PDF]
Yang Y +6 more
europepmc +1 more source
CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su +5 more
wiley +1 more source
Numerical Analysis of the Effects of TPMS Topology and Relative Density on Heat Sink Cooling Performance. [PDF]
Iticha W, Stręk T.
europepmc +1 more source
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
Optimal Design of Large Aperture Primary Mirror of Spaceborne Solar EUV Imager Based on Optomechanical Coupling Analysis. [PDF]
Huang B, Li X, Li Z, Song K.
europepmc +1 more source
Flat Bands Induced by Non‐Collinear Antiferromagnetism in CoBi2Te4
Flat bands emerge at the edges of intrinsically non‐collinear antiferromagnetic CoBi2Te4 two‐septuple layers through the interplay of spin–orbit coupling–driven band inversion and non‐collinear antiferromagnetism, uncovering a previously unexplored mechanism for flat‐band formation and opening new opportunities for strongly correlated quantum states ...
Ziyuan Zhao +4 more
wiley +1 more source
Design- and Voxel-Based Analysis of a Topology-Density Dual-Gradient TPMS Absorber for Impact-Load Mitigation. [PDF]
Xu W +7 more
europepmc +1 more source

