Results 141 to 150 of about 28,679 (285)

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Research on Calculation and Simulating Analysis of Cycloidal Pin Wheel Meshing Stiffness

Jixie chuandong
In order to further improve the load-bearing performance of the RV reducer, a force analysis is conducted on the cycloidal pin wheel pair, regarding the contact stress and meshing stiffness of the cycloidal pin wheel as the research objective functions ...
Su Jianxin, Wang Dongfeng, Xu Jiake, Zhang Jing, Li Hongji, Lü Ruifang   +5 more
doaj   +2 more sources

Identification and proposed control of helicopter transmission noise at the source [PDF]

Helicopter cabin interiors require noise treatment which is expensive and adds weight. The gears inside the main power transmission are major sources of cabin noise.
Coy, John J., Coy, John J., Handschuh, Robert F., Huff, Ronald G., Karchmer, Allan M., Krejsa, Eugene A., Lewicki, David G.   +6 more
core   +2 more sources

A Quantitative Printability Framework for Programmable Assembly of Pre‐Vascular Patterns via Laser‐Induced Forward Transfer

Advanced Healthcare Materials, EarlyView.
Laser‐Induced Forward Transfer (LIFT) is presented as a powerful micropatterning tool. An objective printability framework is developed to assess optimal printing parameter combinations. The technology is further explored for its ability to deterministically deposit microdroplets at predefined locations following CAD designs, enabling the patterning of
Cécile Bosmans, Núria Ginés Rodriguez, Ulisses Jesús Gutiérrez Hernández, David Fernandez Rivas, Marcel Karperien, Jos Malda, Liliana Moreira Teixeira, Riccardo Levato, Jeroen Leijten   +8 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Implementation of a Matrix Crack Spacing Parameter in a Continuum Damage Mechanics Finite Element Model [PDF]

Continuum Damage Mechanics (CDM) based progressive damage and failure analysis (PDFA) methods have demonstrated success in a variety of finite element analysis (FEA) implementations.
Bergan, Andrew, Hyder, Imran, Justusson, Brian P., Leone, Frank A., Schaefer, Joseph D., Wanthal, Steven   +5 more
core   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Research of Internal Excitation of Helical Gear Meshing Transmission

Jixie chuandong, 2018
The internal excitation of gear meshing transmission is the key factor that causes gear vibration and noise. Taking a pair of constant meshing helical gears in an 8-speed automatic transmission as the research object,the internal excitation of meshing ...
Yue Huijun, Song Yuanyuan, Liu Yang, Xu Xiangyang   +3 more
doaj  

Damage Mechanisms in Tapered Composite Structures Under Static and Fatigue Loading [PDF]

In this work an integrated computational/experimental approach was developed to validate the predictive capabilities of State-of-the-Art (SoA) Progressive Damage Analysis (PDA) methods and tools.
Gurvich, Mark R., Palliyaguru, Upul R., Rao, Prabhakar M., Seneviratne, Waruna   +3 more
core   +1 more source