Results 171 to 180 of about 23,412 (303)
Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder
Journal of Internal Medicine, EarlyView.Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley +1 more source
Regional neocortical thinning in mesial temporal lobe epilepsy [PDF]
, 2008 Carrie R. McDonald +7 more
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The Journal of Physiology, EarlyView.Abstract figure legend In this study, we investigated how transporting brain slices influences the electrophysiological and morphological properties of human cortical neurons. Whole‐cell patch‐clamp recordings were obtained from acute slices prepared from tissue collected during epilepsy or tumor surgeries, either on‐site or off‐site, after ...
Guanxiao Qi +7 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.Interictal and ictal discharges in lateral superior parietal lobule epilepsy are predominantly recorded in centroparietal region electrodes. The initial ictal semiology of different parietal lobe epilepsy subregions is distinct and specific, with minimal overlap, reflecting early propagation networks.
Huijuan Wan +11 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.The number of spikes decreased under anesthesia, particularly within the SOZ, while HFOs increased under anesthesia. However, the extent of the increase did not differ between the SOZ and NSOZ. The number of HFOs appeared to be a more reliable interictal biomarker in ioEEG, particularly in the frontal cortex and cingulate cortex, and was not influenced
Chang Liu +8 more
wiley +1 more source
dataset_Deep Learning for the Diagnosis of Mesial Temporal Lobe Epilepsy
, 2022 Kyoya Sakashita
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Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy [PDF]
, 2023 Elena Filimonova +10 more
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Consanguinity in patients with mesial temporal lobe epilepsy due to hippocampal sclerosis in a Saudi population [PDF]
, 2020 Khalid Alqadi +7 more
openalex +1 more source