Historical Risk Factors Associated with Seizure Outcome After Surgery for Drug-Resistant Mesial Temporal Lobe Epilepsy. [PDF]
OBJECTIVE: To investigate the possible influence of risk factors on seizure outcome after surgery for drug-resistant temporal lobe epilepsy (TLE) and mesial temporal sclerosis (MTS).
Asadi-Pooya, Ali Akbar +3 more
core +2 more sources
Clinical, EEG, and MRI Differences in Frontal and Temporal Lobe Epilepsy
Children who underwent video-EEG monitoring between 1995 and 2000, and were classified as frontal lobe epilepsy (FLE) (n=39) or mesial temporal lobe epilepsy (MTLE) (n=17), were examined for clinical, EEG, and quantitative MRI differences, in a study at ...
J Gordon Millichap
doaj +1 more source
The interictal mesial temporal lobe epilepsy network
SummaryObjectiveIdentification of patient‐specific epileptogenic networks is critical to designing successful treatment strategies. Multiple noninvasive methods have been used to characterize epileptogenic networks. However, these methods lack the spatiotemporal resolution to allow precise localization of epileptiform activity.
Suganya, Karunakaran +6 more
openaire +3 more sources
Perirhinal cortex and temporal lobe epilepsy
The perirhinal cortex – which is interconnected with several limbic structures and is intimately involved in learning and memory - plays major roles in pathological processes such as the kindling phenomenon of epileptogenesis and the spread of limbic ...
Giuseppe eBiagini +6 more
doaj +1 more source
Predictors of surgical outcomes in patients with drug-resistant temporal lobe epilepsy
Aim. To identify predictors of surgical outcomes in patients with drug-resistant temporal lobe epilepsy in a multivariate model.Materials and methods.
I. S. Shelyagin +3 more
doaj +1 more source
Spike Frequency and Surgical Outcome in TLE with Unilateral Hippocampal Atrophy
Prognostic implications of absolute spike frequency over the affected temporal lobe and relative spike distribution between the two temporal lobes for postoperative seizure control were assessed in 55 adult patients with medically refractory mesial ...
J Gordon Millichap
doaj +1 more source
Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen +10 more
wiley +1 more source
Disrupted causal connectivity in mesial temporal lobe epilepsy. [PDF]
Although mesial temporal lobe epilepsy (mTLE) is characterized by the pathological changes in mesial temporal lobe, function alteration was also found in extratemporal regions. Our aim is to investigate the information flow between the epileptogenic zone
Gong-Jun Ji +7 more
doaj +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A [PDF]
Epilepsy comprises several syndromes, amongst the most common being mesial temporal lobe epilepsy with hippocampal sclerosis. Seizures in mesial temporal lobe epilepsy with hippocampal sclerosis are typically drug-resistant, and mesial temporal lobe ...
Alhusaini, Saud +70 more
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