Results 261 to 270 of about 128,486 (358)

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Biocompatible Mesoporous Materials for Bone Therapy. [PDF]

Adv Sci (Weinh)
Yu B, Wu Y, Hong Y, Wang P, Liu X, Deng Y, Su J.   +6 more
europepmc   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Cost Evidence Yields the Viability of Metal Oxides Synthesis Routes. [PDF]

ACS Sustain Chem Eng
Gkika DA, Kyzas GZ.
europepmc   +1 more source

Mesoporous silica-based hybrid materials for bone-specific drug delivery

, 2019
Luigi Pasqua, Ilaria Napoli, Marzia De Santo, Marianna Greco, Enrico Catizzone, Domenico Lombardo, Gabriella Montera, Alessandra Comandé, Alessandra Nigro, Catia Morelli, Antonella Leggio   +10 more
openalex   +2 more sources

Phyto‐Confined CeOx with Synergistic Lattice Distortion and Oxygen Vacancies Drives Efficient Urea Electrosynthesis

Advanced Science, EarlyView.
Lattice‐distorted CeOx nanoparticles with abundant oxygen vacancies, confined in porous carbon (d‐CeOx/PC), enable efficient electrocatalytic urea synthesis from CO2 and NO3−. Contracted Ce─O bonds (≈2.29 Å) stabilize OV, creating electron reservoirs for flexible multi‐electron transfer.
Ziming Zhao, Yaru Wei, Haoyu Duan, Yuhan Mei, Huan Li   +4 more
wiley   +1 more source

Evaluating mesoporous zinc oxide nanoparticles for dentin pretreatment: Synthesis, characterization, and bond strength performance with a universal adhesive. [PDF]

Dent Res J (Isfahan)
Jowkar Z, Mostatabi S, Hamidi SA, Moaddeli A.   +3 more
europepmc   +1 more source

Nanoconfinement‐Steered Molecular Preorganization Enables Efficient Monoethanolamine Degradation through Electronically Modulated High‐Valent Iron–Oxo Pathways

Advanced Science, EarlyView.
Precise modulation of reaction pathways remains an unresolved challenge in peroxymonosulfate‐activated advanced oxidation processes. The spatial preorganization strategy in engineered confinement architecture enables regioselective bond cleavage in monoethanolamine via synergistic proton–electron transfer, redirecting its degradation from nonselective ...
Lin Zhang, Qin Dai, Xinyue Chen, Hang Yuan, Lei Xing, Zhimo Fang, Xiuze Li, Xiangke Wang, Lihui Zhang, Junping Zhao, Qiangwei Li, Lidong Wang   +11 more
wiley   +1 more source

Investigation of the Combined Impact of Zinc Oxide Nanoparticles and Bacterial Cellulose Nanocrystals on the Bond Strength to Dentin and Fracture Resistance of Resin-Modified Glass Ionomer Cement in Primary Molars. [PDF]

Clin Exp Dent Res
Nozari A, Parvizi F, Jowkar Z, Haji Abbas Oghli F, Askari H, Hamidi SA.   +5 more
europepmc   +1 more source

Development of micro-mesoporous material of type MCM-22 / MCM-41: synthesis and characterization.

, 2016
Vitória de Andrade. FREIRE
openalex   +1 more source