Results 71 to 80 of about 33,388 (264)

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Synergistic p53 Pathway Activation Through Sono‐Gene Therapy Induced by Ultrasound‐Triggered Theranostic Mesoporous Nanoparticles

Advanced Science, EarlyView.
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Song Ning, Shuting Huang, Xiaoxuan Wang, Rui Liu, Yuye Fu, Suyun Li, Jie Li   +11 more
wiley   +1 more source

Preparation and Characterization of Sulpho-Functionalized Ordered Mesoporous Silica

Adsorption Science & Technology, 2008
Sulpho groups have been successfully embedded in mesoporous silica with an ordered two-dimensional hexagonal structure. The sulpho-functionalized mesoporous silica was prepared by the oxidation of a thiol-functionalized mesoporous silica which was ...
Fei-Yee Yeoh, Akihiko Matsumoto, Yoshiyuki Iwase, Toshihide Baba   +3 more
doaj   +1 more source

Self‐Assembly of Organic–Inorganic Copolymers Toward Bio‐Inspired Cementitious Composites

Advanced Science, EarlyView.
Organic–inorganic copolymerization of calcium silicate hydrate and thioctic acid produces a self‐organized nanocomposite inspired by the disordered collagen–mineral architecture of trabecular bone. The resulting material combines a compressive strength above 300 MPa with intrinsic physical reprocessibility, retaining over 80% of its strength and energy
Zonglin Xie, Suning Li, Fuwen Zhong, Gongkun Xiang, Mustapha Jamaa Garba, Yi Tian, Jun Wu, Zhiwu Yu, Qiang Yuan   +8 more
wiley   +1 more source

Preparation of a Double-Layered Composite Film Loaded with Cinnamic Acid@Mesoporous Silica and Its Application in Blueberry Preservation [PDF]

Shipin Kexue
This study developed a double-layered active packaging film based on chitosan and zein loaded with cinnamic acid@mesoporous silica and nano-silica.
HUANG Duanying, ZHENG Jianxian
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Synthesis and morphological characterisation of mesoporous biosilica from oil palm male inflorescence

Discover Chemistry
With the increasing demand for mesoporous silica in various applications couple with the high cost of silica precursors and the environmental implications associated with the synthetic mesoporous silica, there is a pressing need for sustainable ...
Sunday Mathew Ajayi, Samuel Olalekan Olusanya, Sunday Felix Abimbade, Emmanuel Gbenga Olumayede, Abdulhakeem Dapo Olasupo   +4 more
doaj   +1 more source

Programmed Interfacial Phase Separation for Spatiotemporal Fungicide Delivery via Tunable Micro/Nano Architectures

Advanced Science, EarlyView.
ABSTRACT Translating dynamic liquid‐liquid phase separation into robust solid‐state architectures remains a challenge in materials engineering. Here, we report a composition‐driven interfacial assembly strategy that couples supramolecular coacervation with metal‐phenolic coordination to engineer tunable fungicide carriers.
Rui Zhang, Tongfang Jing, Leiming He, Kaidi Cui, Yuying Song, Xuewei Mao, Lidong Cao, Lin Zhou   +7 more
wiley   +1 more source

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

Advanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou, Xiaoxue Zhu, Runhan Zhu, Chengchu Xue, Qinyu Zhang, Mengke Li, Ting Yu, Yuzhen Gao, Zhi Ruan, Ying Fu, Yunlei Xianyu, Jun Zhang   +11 more
wiley   +1 more source

Advancing malaria treatment with magnetic and mesoporous silica nanoparticles loaded with sulfadoxine-pyrimethamine: a review

Discover Nano
Malaria remains a pressing global health concern, particularly in regions with rising cases of drug-resistant Plasmodium strains. Sulphadoxine-pyrimethamine (SP), a widely used antimalarial drug combination, faces challenges such as reduced ...
Tsegaye Fekadu Egza, Eyob Mulugeta Kebede, Ramesh Duraisamy Perumal   +2 more
doaj   +1 more source