Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicines [PDF]
Nanoparticles have become a powerful tool in oncology not only as carrier of the highly toxic chemotherapeutic drugs but also as imaging contrast agents that provide valuable information about the state of the disease and its progression. The enhanced permeation and retention effect for loaded nanocarriers in tumors allow substantial improvement of ...
Alejandro Baeza, Maria Vallet-Regí
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Mesoporous Silica Nanoparticles With Customized Drug Ratio/Loading for Effective Treatment of Gemcitabine-Resistant Pancreatic Tumors. [PDF]
Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Huq TB +5 more
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Atom Transfer Radical Polymerization of Styrene in Presence of Mesoporous Silica Nanoparticles: Application of Reverse, Simultaneous Reverse and Normal Initiation Techniques [PDF]
Atom transfer radical polymerization (ATRP) of styrene in presence of mesoporous silica nanoparticles was carried out at 110 °C. Reverse atom transfer radical polymerization (RATRP) and simultaneous reverse and normal initiation for atom transfer radical
Khezrollah Khezri +3 more
doaj +1 more source
Fluorogenic Detection of Human Serum Albumin Using Curcumin-Capped Mesoporous Silica Nanoparticles
Mesoporous silica nanoparticles loaded with rhodamine B and capped with curcumin are used for the selective and sensitive fluorogenic detection of human serum albumin (HSA).
Ismael Otri +4 more
doaj +1 more source
Mesoporous silica nanoparticles (MSNs) are widely used as a promising candidate for drug delivery applications due to silica’s favorable biocompatibility, thermal stability, and chemical properties.
Parya Kazemzadeh +6 more
semanticscholar +1 more source
Environmentally friendly synthesis of nanoporous silica materials using quercetin as a morphogenetic agent [PDF]
BACKGROUND AND OBJECTIVES: The synthesis of mesoporous silica nanoparticles using non-surfactant agents is gaining popularity owing to the easier purification and lower toxicity of this method compared to traditional surfactant-based ones.
A.R. Zare Hoseinabadi +8 more
doaj +1 more source
Objective: To explore the inhibitory and synergistic effects of 5-fluorouracil and curcumin on Hep-2 laryngeal cancer cells and clarify the effect of mesoporous silica nanoparticles as drug carriers.
Ding Wang PhD +9 more
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Mesoporous organosilica nanoparticles: Degradation strategies and application in tumor therapy
Biodegradation is a crucial issue for silica‐based mesoporous nanoparticles that is related to the biosafety in tumor therapy. Nowadays, mesoporous silica nanoparticles (MSNs) have been intensively developed to construct multifunctional nanosystems for ...
Lei Guan +5 more
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Osteoporosis Remission and New Bone Formation with Mesoporous Silica Nanoparticles
Nanotechnology changed the concept of treatment for a variety of diseases, producing a huge impact regarding drug and gene delivery. Among the different targeted diseases, osteoporosis has devastating clinical and economic consequences.
P. Mora-Raimundo +5 more
semanticscholar +1 more source
Mesoporous silica nanoparticles as nanocarriers
Modern nanomedicine aims at delivering drugs or cells specifically to defective cells; therefore, this calls for developing multifunctional nanocarriers for drug delivery and cell-tracking. Mesoporous silica nanoparticles (MSNs) are well suited for this task. In this feature article, we highlight the strategies in the synthesis and functionalization of
Wu, Si-Han, Hung, Yann, Mou, Chung-Yuan
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