Results 131 to 140 of about 110,409 (295)
The Role of RANBP3L in Pan‐Cancer With Its Significance in Hepatocellular Carcinoma
Cancer Reports, Volume 9, Issue 1, January 2026.ABSTRACT Background RAN binding protein 3‐like (RANBP3L), a member of the Ran‐binding protein family, has been linked to various cellular functions, but the role in cancer remains underexplored. In this research, we assessed the diagnostic and prognostic value of RANBP3L in pan‐cancer, especially in liver hepatocellular carcinoma (LIHC).
Beini Cen, Jie Li, Chao Wang
wiley +1 more source
Downregulation of TNFAIP3 Associated With Poor Prognosis and Immune Response in Breast Cancer
Cancer Reports, Volume 9, Issue 1, January 2026.ABSTRACT Background Breast cancer (BRCA) progression is closely linked to dysregulated inflammatory processes within the tumor microenvironment (TME). TNFAIP3, a key regulator of TNF‐α signaling, plays a dual role in cancer biology, but its precise function in BRCA pathogenesis and immune modulation remains unclear.
Yeqin Wu, Zhaoyang Qin, Gangping Wang
wiley +1 more source
What's Your Diagnosis? Large Mediastinal Mass in a Dog
Veterinary Clinical Pathology, EarlyView.
Rosane O. Cruz +7 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.DCAF7 is up‐regulated in various tumours and correlates with poor prognosis, particularly in LIHC. High DCAF7 expression is linked to CD4+ T cell infiltration, up‐regulation of immune checkpoint genes and increased tumour mutational burden, suggesting a role in tumour immune escape.
Ruina Luan +6 more
wiley +1 more source
The Role of Macrophages in Cancer: From Basic Research to Clinical Applications
MedComm, Volume 7, Issue 1, January 2026.Monocytes infiltrate the tumor microenvironment (TME) and differentiate into macrophages, which polarize into proinflammatory, antitumor M1 cells or immunosuppressive, protumor M2 cells. Within the TME, M2‐type tumor‐associated macrophages (TAMs) predominate and drive tumor growth, angiogenesis, and metastasis. Therapeutic strategies therefore focus on
Zhimei Liu +5 more
wiley +1 more source
Melanoma: Pathogenesis and Targeted Therapy
MedComm, Volume 7, Issue 1, January 2026.The treatment landscape for advanced melanoma has evolved significantly. BRAF–MEK inhibitor combinations are standard for BRAF‐mutant melanoma, whereas targeting NRAS mutations is more challenging, with MEK inhibitors like tunlametinib emerging as an option.
Yang Fu +5 more
wiley +1 more source
Frontiers in OncologyThe malignant mesothelioma mainly develops in the pleura and peritoneum, while primary ovarian mesothelioma is very rare. Here, we report the first case of primary ovarian mesothelioma (clear cell variant) with VHL mutations in the world based on the ...
Ye Yao, Hao Yan, Jing Xiong, Yaqi Duan
doaj +1 more source
Pleurectomy decortication is the preferred surgical procedure in pleural mesothelioma [PDF]
, 2023 Moshe Lapidot, Raphael Bueno
openalex +1 more source
Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management
Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh +4 more
wiley +1 more source
Effusion‐Dominant Pulmonary Sarcomatoid Carcinoma Without a Primary Mass: A Case Report
Respirology Case Reports, Volume 14, Issue 1, January 2026.We describe a patient with high‐grade sarcomatoid carcinoma presenting as malignant pleural effusion without a primary mass. This case highlights the diagnostic challenges, aggressive clinical course, and importance of early biopsy. We also review the limited literature describing similar presentations.
Sze Kye Teoh +5 more
wiley +1 more source