Results 141 to 150 of about 57,565 (259)
Integrating polygenic and methylation risk scores for pleural mesothelioma risk stratification
International Journal of Cancer, Volume 158, Issue 11, Page 2866-2879, 1 June 2026.What's new? Asbestos exposure is a major risk factor for pleural mesothelioma (PM). Most asbestos‐exposed individuals do not develop PM, suggesting that it arises from a complex interplay between environmental and genetic factors. This study examined the utility of polygenic risk scores (PRS) and methylation risk scores (MRS) in incorporating genetic ...
Khadija Sana Hafeez +26 more
wiley +1 more source
New Zealand Journal of Geology and Geophysics, Volume 69, Issue 2, June 2026.Mordenite is a naturally occurring zeolite mineral that is the seventh most common zeolite mineral globally, forming at low temperatures (≥100°C) in hydrothermal systems. In New Zealand, extensive deposits of mordenite are commonly associated with areas of hydrothermal alteration, particularly in the Coromandel and Taupo Volcanic Zones.
Ayrton R. Hamilton +6 more
wiley +1 more source
Veterinary Record Open, Volume 13, Issue 1, June 2026.Abstract Background Animal cancer registry data are important for monitoring animal health, for prevention and research in veterinary medicine, and for comparative oncology. Since people and animals share the same environment and are exposed to many common risk factors, cancer patterns in animals may have a sentinel function for human health.
Claudio Trentin +10 more
wiley +1 more source
Scientific ReportsMalignant mesothelioma, a highly aggressive cancer that primarily affects the serosal membranes, has limited therapeutic options, particularly for cavitary tumors, such as peritoneal and pleural malignant mesothelioma.
Kim Lindland +6 more
doaj +1 more source
Clinical and Translational Science, Volume 19, Issue 6, June 2026.ABSTRACT Drug‐induced kidney injury should be monitored throughout the drug development process to ensure patient safety. Standard kidney injury biomarkers may not always correlate with subtle microscopic histopathological kidney injury. Standard biomarkers are insufficiently sensitive for detection of early‐phase kidney injury.
Takehiko Sambe +7 more
wiley +1 more source
Clinical and Translational Science, Volume 19, Issue 6, June 2026.ABSTRACT Despite advances in novel therapeutic modalities, such as molecularly targeted agents and immunotherapies, the probability of success in Phase III oncology trials remains low. This study quantitatively characterized success probabilities of Phase III trials in oncology drug development and evaluated the factors associated with trial success ...
Keiko Yamamoto, Aya Iwase, Hideki Maeda
wiley +1 more source
Mesothelioma is a lethal cancer of the serosal lining of the body cavities. Risk factors include environmental and genetic factors. Asbestos exposure is considered the principal environmental risk factor, but other carcinogenic mineral fibers, such as ...
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, 2007 Italy was an important producer of raw asbestos until 1992 (when it was banned) and it is now experiencing severe public health consequences due to large-scale industrial use of asbestos in shipbuilding and repair, asbestos-cement production, railways ...
MIRABELLI D +19 more
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