Results 171 to 180 of about 107,800 (308)

Repurposing the Antidepressant Sertraline: A Systematic Scoping Review of Its Anticancer Mechanisms

Pharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
A multi‐targeted antidepressant with strong preclinical anticancer activity, sertraline represents a candidate for therapeutic repurposing. ABSTRACT Drug repurposing offers a cost‐effective and time‐efficient strategy for identifying new cancer therapies. Sertraline, a widely prescribed selective serotonin reuptake inhibitor (SSRI), has shown promising
Ciara B. Blum, McCarlie‐Jayne Dohrmann, Lucia McCarthy, Milli McMenamin, Liam A. O'Callaghan   +4 more
wiley   +1 more source

Myeloid Cell Mobilization and Recruitment by Human Mesothelioma in NSG-SGM3 Mice

Cells
Malignant pleural mesothelioma is a neoplasm that is often detected late due to nonspecific symptoms. This study utilized NSG-SGM3 mice to examine interactions between a human-derived mesothelioma reporter cell line (MZT-Luc2-mCherry) and the host’s ...
Vadim V. Shindyapin, Ekaterina O. Gubernatorova, Ekaterina A. Gorshkova, Nelya R. Chicherina, Fedor A. Sysonov, Anastasia S. Yakovleva, Daria A. Bogdanova, Oleg N. Demidov, Mariya V. Samsonova, Vladimir P. Baklaushev, Gaukhar M. Yusubalieva, Marina S. Drutskaya   +11 more
doaj   +1 more source

Epidemiology of pleural mesothelioma in North-western Italy (Piedmont) [PDF]

, 1972
Giovanni Rubino, G Scansetti, A Donna, Giorgio Palestro   +3 more
openalex   +1 more source

Antigen targeting and anti-tumor activity of a novel anti-CD146 212Pb internalizing alpha-radioimmunoconjugate against malignant peritoneal mesothelioma

Scientific Reports
Malignant mesothelioma, a highly aggressive cancer that primarily affects the serosal membranes, has limited therapeutic options, particularly for cavitary tumors, such as peritoneal and pleural malignant mesothelioma.
Kim Lindland, Marion Masitsa Malenge, Ruth Gong Li, Roxanne Wouters, Tina Bjørnlund Bønsdorff, Asta Juzeniene, Srdan M. Dragovic   +6 more
doaj   +1 more source

Mesotheliomas in rats following inoculation with asbestos.

, 1969
J. C. Wagner, Geoffrey Berry
openalex   +2 more sources

Relationship between occupations and asbestosfibre content of the lungs in patients with pleural mesothelioma, lung cancer, and other diseases [PDF]

, 1977
F. Whitwell, J.K. Scott, M. Grimshaw
openalex   +1 more source

Immunodiagnosis of mesothelioma. Use of antimesothelial cell serum in an indirect immunofluorescence assay [PDF]

, 1979
Gurmukh Singh, Theresa L. Whiteside, Andrew Dekker   +2 more
openalex   +1 more source

Synthetic Biology and Biomaterials Strategies to Deceive the Tumor Microenvironment in CAR‐T Immunotherapy

Small, Volume 21, Issue 39, October 2, 2025.
A. Synthetic biology and biomaterials have emerged as tools to study and facilitate the treatment of solid tumors wi‐th chimeric antigen receptor‐CAR‐T cells. These strategies aim to resist the tumor microenvironment‐TME that presents cellular, biochemical, and mechanical immunosuppressive signals that hinder CAR‐T efficacy. B.
Grazia Marsico, Sudarshan GC, Velia Siciliano   +2 more
wiley   +1 more source

Intrinsic PDL1 Signaling Modulates TGFBI‐Mediated Growth Suppression in Lung Adenocarcinoma

Cancer Science, Volume 116, Issue 10, Page 2737-2749, October 2025.
Programmed death ligand 1 (PDL1) is known for suppressing T‐cell immunity, but its intrinsic role in oncogenesis remains unclear. This study demonstrates that PDL1 expression in lung adenocarcinoma (ADC) inhibits tumor cell growth by reducing FAK activation and regulating the CITED2‐p21CIP1 axis, leading to cell growth arrest.
Thi Thanh Nha Nguyen, Pei‐Yu Chen, Ming‐Yi Zheng, Ting‐Kuang Lin, Chun‐Chao Wang, Yuh‐Min Chen, Yu‐Ting Chou   +6 more
wiley   +1 more source

Two malignant pleural mesotheliomas with unusual histological features. [PDF]

, 1979
B. Goldstein
openalex   +1 more source