Results 181 to 190 of about 111,076 (331)
The Thoracic Lymphatic Vasculature: Interorgan Strategies to Achieve an Optimal Tissue Function
In the thorax, organ‐specific features such as stomata and submesothelial lacunae, pulmonary perivascular and peribronchial vessels, and subepicardial lymphatic network allow the thoracic lymphatics to perform as a dynamically regulated system able to exploit local mechanical forces and tissue‐specific architecture to maintain fluid and solute ...
Daniela Negrini +3 more
wiley +1 more source
Spatial omics for profiling the dynamic tumor microenvironment
Spatially resolved transcriptomics and proteomics map RNA/protein in intact tumor tissues, revealing crucial cancer–immune interactions across the different stages of tumor evolution. Integrating AI promises translational impact, but gaps in cross‐platform integration, standards, compute, validation and interpretability remain.
Hao Nguyen +3 more
wiley +1 more source
Data Supplement from Nonamplified FGFR1 Is a Growth Driver in Malignant Pleural Mesothelioma
Lindsay A. Marek +12 more
openalex +1 more source
PVT1‐104aa derived from the 8q24 gene desert promotes colorectal cancer tumorigenesis
The schematic illustrates the dual oncogenic mechanism of circPVT1‐encoded PVT1‐104aa in CRC. First, MYC stabilization: (1) Direct binding to MYC; (2) phosphorylation of MYC at Ser62; (3) protection from GSK3β/FBW7‐mediated ubiquitination. Second, immunomodulation: (1) MYC‐dependent PD‐L1 upregulation; (2) enhanced therapeutic efficacy when combining ...
Maoguang Ma +9 more
wiley +1 more source
ABSTRACT Malignant mesothelioma (MM) is a rare yet aggressive neoplasm that arises from mesothelial cells lining the thoracic and abdominal cavities, the pericardium, and the tunica testis. Characterized by rapid progression, high invasiveness, and a poor prognosis, MM poses significant clinical challenges. SMARCB1, also referred to as INI‐1, hSNF5, or
Jun Yang +4 more
wiley +1 more source
Comment on 'The latency period of mesothelioma among a cohort of British asbestos workers (1978-2005)': methodological problems with case-only survival analysis. [PDF]
A Marinaccio +13 more
core +2 more sources

