Results 111 to 120 of about 257,181 (321)
Translation of the tryptophan messenger RNA of Escherichia coli. [PDF]
, 1968 Daniel E. Morse +2 more
openalex +1 more source
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development
Advanced Science, EarlyView.The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao +9 more
wiley +1 more source
Construction of Large‐Scale Bioengineered Hair Germs and In Vivo Transplantation
Advanced Science, EarlyView.Here, a novel bioengineered hair germ (BHG) system is developed using thermodynamically incompatible mucopolysaccharides for efficient hair follicle regeneration. The BHG microspheres, produced via microfluidic technology, encapsulate Wnt3a for sustained release, enhancing mesenchymal stem cell differentiation and activating key regeneration pathways ...
Yangpeng Chen +8 more
wiley +1 more source
Mesenchymal stem cells: A novel treatment option for primary sclerosing cholangitis
Cell Biology International, Volume 47, Issue 2, Page 467-479, February 2023., 2023 Abstract Primary sclerosing cholangitis (PSC) is a progressive liver disease for which there is no effective therapy. Hepatocytes and cholangiocytes from a PSC patient were cocultured with mesenchymal stem cells (MSCs) to assess in vitro change. A single patient with progressive PSC was treated with 150 million MSCs via direct injection into the common
Amy L. Lightner +8 more
wiley +1 more source
DEMONSTRATION OF THE MESSENGER ROLE OF VIRAL RNA [PDF]
, 1962 Akira Tsugita +3 more
openalex +1 more source
Advanced Science, EarlyView.The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi +8 more
wiley +1 more source
Semi-Markov models of mRNA-translation [PDF]
arXiv, 2011 Translation is the cellular process in which ribosomes make proteins from information encoded on messenger RNA (mRNA). We model translation with an exclusion process taking into account the experimentally determined, non-exponential, waiting time between steps of a ribosome.
arxiv
THE SYNTHESIS OF MESSENGER RNA WITHOUT PROTEIN SYNTHESIS IN NORMAL AND PHAGE-INFECTED THYMINELESS STRAINS OF ESCHERICHIA COLI [PDF]
, 1963 Shira Cohen +3 more
openalex +1 more source
Advanced Science, EarlyView.RNA modification is crucial in fibrosis diseases, but the role of m1A modification remains elusive. This study reveals that ALKBH3, an m1A demethylase, drives skin fibrosis by reshaping m6A RNA modification and stabilizing COL1A1 and FN1 mRNAs through METTL3, uncovering a crosstalk between m1A and m6A methylation in pathological events.
Liying Tu +9 more
wiley +1 more source
Journal of Asthma and Allergy, 2023 Ting-Yu Lin,1,2 Chun-Yu Lo,1,2 Po-Jui Chang,1,2 Yu-Lun Lo,1,2 Chung-Shu Lee,1– 3 Chih-Hao Chang,1– 3 Chih-Teng Yu,1,2 Jonathan Huai Yao,1 Shu-Min Lin1,2 1Department of Thoracic Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan; 2College of Medicine,
Lin TY +8 more
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